Acoustic radiation force impulse (ARFI) elastography of the bowel wall as a possible marker of inflammatory activity in patients with Crohn's disease

Görtz R, Lueke C, Wildner D, Vitali F, Neurath M, Strobel D (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Clinical Radiology WB Saunders

Book Volume: 73

Pages Range: 678.e1-678.e5

Journal Issue: 7

DOI: 10.1016/j.crad.2018.02.005

Abstract

AIM: To evaluate acoustic radiation force impulse (ARFI) shear-wave velocities of the bowel wall in patients with Crohn's disease (CD). MATERIAL AND METHODS: ARFI shear-wave elastography was analysed within the wall of the stomach, terminal ileum, and sigmoid, and correlated with ultrasound signs of activity in CD patients both retrospectively and in a prospective cohort. RESULTS: A total of 77 retrospective and 21 prospective CD patients were included. ARFI elastography in the stomach, the normal ileum, and sigmoid was lower than in ileitis or sigmoiditis. Retrospectively, the ARFI values correlated with the bowel wall thickness and Limberg vascularisation score. Prospectively, there was no correlation between ARFI and bowel wall thickness, Limberg score, clinical activity, or C-reactive protein. A cut-off analysis of 105 ileal ARFI measurements showed a cut-off value of 1.92 m/s for the diagnosis of ileal inflammation with 75.3% sensitivity and 87.5% specificity. CONCLUSION: In patients with CD, ARFI shear-wave velocities show a trend to higher values in inflamed bowel wall thickening on B-mode ultrasound; however, the differences appear small and may not be clinically significant. The factors influencing ARFI measurements of the bowel wall require further investigation.

Authors with CRIS profile

Rüdiger Görtz Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Dane Wildner Medizinische Fakultät Francesco Vitali Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Markus Neurath Lehrstuhl für Innere Medizin I Deike Strobel Medizinische Fakultät

How to cite

APA:

Görtz, R., Lueke, C., Wildner, D., Vitali, F., Neurath, M., & Strobel, D. (2018). Acoustic radiation force impulse (ARFI) elastography of the bowel wall as a possible marker of inflammatory activity in patients with Crohn's disease. Clinical Radiology, 73(7), 678.e1-678.e5. https://doi.org/10.1016/j.crad.2018.02.005

MLA:

Görtz, Rüdiger, et al. "Acoustic radiation force impulse (ARFI) elastography of the bowel wall as a possible marker of inflammatory activity in patients with Crohn's disease." Clinical Radiology 73.7 (2018): 678.e1-678.e5.

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