Whither systems medicine?

Journal article


Publication Details

Author(s): Apweiler R, Beissbarth T, Berthold MR, Bluethgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Hoefer T, Jansen PLM, Kaderali L, Klingmueller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O
Journal: Experimental and Molecular Medicine
Publication year: 2018
Volume: 50
Journal issue: 3
ISSN: 1226-3613


Abstract

New technologies to generate, store and retrieve medical and research data are inducing a rapid change in clinical and translational research and health care. Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from biology, biostatistics, informatics, mathematics and computational modeling to develop methods to use new and stored data to the benefit of the patient. We here provide a critical assessment of the opportunities and challenges arising out of systems approaches in medicine and from this provide a definition of what systems medicine entails. Based on our analysis of current developments in medicine and healthcare and associated research needs, we emphasize the role of systems medicine as a multilevel and multidisciplinary methodological framework for informed data acquisition and interdisciplinary data analysis to extract previously inaccessible knowledge for the benefit of patients.


FAU Authors / FAU Editors

Vera González, Julio Prof. Dr.
Professur für Tumorimmunologie (Schwerpunkt Systembiologie)


External institutions
Biologische Heilmittel Heel GmbH
Biomax Informatics AG
Charité - Universitätsmedizin Berlin
Christian-Albrechts-Universität zu Kiel
Deutsches Krebsforschungszentrum (DKFZ)
Eberhard Karls Universität Tübingen
Goethe-Universität Frankfurt am Main
Hannover Medical School / Medizinische Hochschule Hannover (MHH)
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU)
Justus-Liebig-Universität Gießen
Maastricht University
Max Planck Institute for Informatics / Max-Planck-Institut für Informatik
Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen
Technische Universität Dresden
The European Bioinformatics Institute (EBI)
Tufts University
Universität des Saarlandes (UdS)
Universität Konstanz
Universität Leipzig
Universität Rostock
Universitätsklinikum Göttingen
Universitätsklinikum Heidelberg
Universitätsmedizin Greifswald / Universitätsklinikum Greifswald
Universität Stuttgart


How to cite

APA:
Apweiler, R., Beissbarth, T., Berthold, M.R., Bluethgen, N., Burmeister, Y., Dammann, O.,... Wolkenhauer, O. (2018). Whither systems medicine? Experimental and Molecular Medicine, 50(3). https://dx.doi.org/10.1038/emm.2017.290

MLA:
Apweiler, Rolf, et al. "Whither systems medicine?" Experimental and Molecular Medicine 50.3 (2018).

BibTeX: 

Last updated on 2018-30-11 at 08:53