Innovative Toxicological Investigation Methods for Iron Oxide Nanoparticles in Nanomedicine

Journal article


Publication Details

Author(s): Janko C, Pöttler M, Matuszak J, Unterweger H, Hornung A, Friedrich RP, Alexiou C
Journal: Chemie Ingenieur Technik
Publication year: 2017
Volume: 89
Journal issue: 3
Pages range: 244-251
ISSN: 0009-286X


Abstract

Superparamagnetic iron oxide nanoparticles (SPIONs) offer various possibilities for application in medicine. Comprehensive toxicological investigations based on proper physicochemical nanoparticle characterizations are a prerequisite for translation from bench to bedside. Since nanoparticles are prone to interfere with several classical toxicological readout systems, alternative methods are necessary. Multiparameter stainings for flow cytometry and fluorescence microscopy, label-free real-time cell analyses, 3D cell culture, and flow models will be discussed here.


FAU Authors / FAU Editors

Alexiou, Christoph Prof. Dr.
Professur für Nanomedizin
Hornung, Annkathrin
Frauenklinik
Janko, Christina Dr. rer. nat.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Matuszak, Jasmin
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Unterweger, Harald Dr.-Ing.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie


How to cite

APA:
Janko, C., Pöttler, M., Matuszak, J., Unterweger, H., Hornung, A., Friedrich, R.P., & Alexiou, C. (2017). Innovative Toxicological Investigation Methods for Iron Oxide Nanoparticles in Nanomedicine. Chemie Ingenieur Technik, 89(3), 244-251.

MLA:
Janko, Christina, et al. "Innovative Toxicological Investigation Methods for Iron Oxide Nanoparticles in Nanomedicine." Chemie Ingenieur Technik 89.3 (2017): 244-251.

BibTeX: 

Last updated on 2018-12-11 at 13:08