Innovative Toxicological Investigation Methods for Iron Oxide Nanoparticles in Nanomedicine

Janko C, Pöttler M, Matuszak J, Unterweger H, Hornung A, Friedrich RP, Alexiou C (2017)


Publication Type: Journal article

Publication year: 2017

Journal

Book Volume: 89

Pages Range: 244-251

Journal Issue: 3

Abstract

Superparamagnetic iron oxide nanoparticles (SPIONs) offer various possibilities for application in medicine. Comprehensive toxicological investigations based on proper physicochemical nanoparticle characterizations are a prerequisite for translation from bench to bedside. Since nanoparticles are prone to interfere with several classical toxicological readout systems, alternative methods are necessary. Multiparameter stainings for flow cytometry and fluorescence microscopy, label-free real-time cell analyses, 3D cell culture, and flow models will be discussed here.

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How to cite

APA:

Janko, C., Pöttler, M., Matuszak, J., Unterweger, H., Hornung, A., Friedrich, R.P., & Alexiou, C. (2017). Innovative Toxicological Investigation Methods for Iron Oxide Nanoparticles in Nanomedicine. Chemie Ingenieur Technik, 89(3), 244-251.

MLA:

Janko, Christina, et al. "Innovative Toxicological Investigation Methods for Iron Oxide Nanoparticles in Nanomedicine." Chemie Ingenieur Technik 89.3 (2017): 244-251.

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