Innovative Methods and Applications in Mucoadhesion Research

Journal article

Publication Details

Author(s): Mackie AR, Goycoolea FM, Menchicchi B, Caramella CM, Saporito F, Lee S, Stephansen K, Chronakis IS, Hiorth M, Adamczak M, Waldner M, Nielsen HM, Marcelloni L
Journal: Macromolecular Bioscience
Publication year: 2017
Volume: 17
Journal issue: 8
ISSN: 1616-5187


The present review is aimed at elucidating relatively new aspects of mucoadhesion/mucus interaction and related phenomena that emerged from a Mucoadhesion workshop held in Munster on 2-3 September 2015 as a satellite event of the ICCC 13th-EUCHIS 12th. After a brief outline of the new issues, the focus is on mucus description, purification, and mucus/mucin characterization, all steps that are pivotal to the understanding of mucus related phenomena and the choice of the correct mucosal model for in vitro and ex vivo experiments, alternative bio/mucomimetic materials are also presented. Then a selection of preparative techniques and testing methods are described (at molecular as well as micro and macroscale) that may support the pharmaceutical development of mucus interactive systems and assist formulators in the scale-up and industrialization steps. Recent applications of mucoadhesive systems (including medical devices) intended for different routes of administration (oral, gastrointestinal, vaginal, nasal, ocular, and intravesical) and for the treatment of difficult to treat pathologies or the alleviation of symptoms are described.

FAU Authors / FAU Editors

Menchicchi, Bianca Dr.
Erlangen Graduate School in Advanced Optical Technologies
Waldner, Maximilian Prof. Dr.
Lehrstuhl für Innere Medizin I

External institutions with authors

S.I.I.T. S.r.l.
Technical University of Denmark / Danmarks Tekniske Universitet (DTU)
Università degli Studi di Pavia
University of Copenhagen
University of East Anglia
University of Leeds
University of Oslo

How to cite

Mackie, A.R., Goycoolea, F.M., Menchicchi, B., Caramella, C.M., Saporito, F., Lee, S.,... Marcelloni, L. (2017). Innovative Methods and Applications in Mucoadhesion Research. Macromolecular Bioscience, 17(8).

Mackie, Alan R., et al. "Innovative Methods and Applications in Mucoadhesion Research." Macromolecular Bioscience 17.8 (2017).


Last updated on 2018-09-11 at 13:08