Anatomical locations in the oral cavity where surgical resections of oral squamous cell carcinomas are associated with a close or positive margin-a retrospective study
Beitrag in einer Fachzeitschrift
Details zur Publikation
Autorinnen und Autoren: Kerker F, Adler W, Brunner K, Moest T, Wurm M, Nkenke E, Neukam FW, von Wilmowsky C
Zeitschrift: → Clinical Oral Investigations |
Jahr der Veröffentlichung: 2018
Band: 22
Heftnummer: 4
Seitenbereich: 1625-1630
ISSN: 1432-6981
Abstract
OBJECTIVES: This study aimed to identify anatomical areas where resections of oral squamous cell carcinomas (OSCC) are significantly associated with close or positive margins.
MATERIALS AND METHODS: This retrospective study included 330 patients with a primary OSCC from 2010 to 2015. Patient and tumour data were categorised into three groups by R-status (R0 [clear], ≥ 5 mm, 185 patients [56.06%]; R1 [positive], < 1 mm, 24 patients [7.27%]; and R0 [close], 1-5 mm, 121 patients [36.67%]).
RESULTS: Areas where resections were significantly associated with close or positive margins were the hard palate (p < 0.001), buccal mucosa (p = 0.03), floor of the mouth (p = 0.004), lower alveolar ridge (p = 0.01), retromolar triangle (p = 0.005), and dorsal tongue (p = 0.02).
CONCLUSIONS: Anatomical areas were identified in the oral cavity where it is challenging to resect OSCCs with an adequate safety margin.
CLINICAL RELEVANCE: These results may enable surgeons to achieve a postulated safe distance during tumour resection, leading to a survival benefit for patients.
FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber
| | | Lehrstuhl für Biometrie und Epidemiologie |
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| | | Lehrstuhl für Zahnmedizin, insbesondere Mund-, Kiefer-, und Gesichtschirurgie |
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| Neukam, Friedrich Wilhelm Prof. Dr. Dr. |
| | Lehrstuhl für Zahnmedizin, insbesondere Mund-, Kiefer-, und Gesichtschirurgie |
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| von Wilmowsky, Cornelius PD Dr. |
| | Mund-, Kiefer- und Gesichtschirurgische Klinik |
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| | | Mund-, Kiefer- und Gesichtschirurgische Klinik |
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Einrichtungen weiterer Autorinnen und Autoren
→ Medizinische Universität Wien |
Zitierweisen
APA: | Kerker, F., Adler, W., Brunner, K., Moest, T., Wurm, M., Nkenke, E.,... von Wilmowsky, C. (2018). Anatomical locations in the oral cavity where surgical resections of oral squamous cell carcinomas are associated with a close or positive margin-a retrospective study. Clinical Oral Investigations, 22(4), 1625-1630. https://dx.doi.org/10.1007/s00784-018-2424-z |
MLA: | Kerker, Florian, et al. "Anatomical locations in the oral cavity where surgical resections of oral squamous cell carcinomas are associated with a close or positive margin-a retrospective study." Clinical Oral Investigations 22.4 (2018): 1625-1630. |