Assessment of edema using STIR+ via 3D cardiovascular magnetic resonance imaging in patients with suspected myocarditis

Jeserich M, Merkely B, Schlosser P, Kimmel S, Pavlik G, Achenbach S (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Magnetic Resonance Materials in Physics Biology and Medicine Springer Verlag (Germany)

Book Volume: 30

Pages Range: 309-316

Journal Issue: 3

DOI: 10.1007/s10334-016-0603-y

Abstract

OBJECTIVE: To evaluate three-dimensional T2-weighted fast spin echo triple inversion recovery sequences (STIR+) for the diagnosis of myocardial edema in patients with suspected early myocarditis after respiratory or gastrointestinal tract viral infection and at follow-up. MATERIALS AND METHODS: We prospectively examined 28 patients with suspected myocarditis and 37 controls matched for gender and age. An ECG-triggered STIR+ was used to cover the entire left ventricle in short-axis images with 10-mm slice thickness and no interslice gap. The global signal intensity ratio (heart muscle in relation to skeletal muscle) was calculated (global STIR+ ratio) to evaluate edema. All patients had repeat examinations at follow-up (mean interval 4.9 months, 1-12 months). RESULTS: The mean global STIR+ ratio was 2.15 ± 0.4 in the initial examination of patients as compared to 1.78 ± 0.3 in controls (p < 0.0001) and 1.89 ± 0.3 in patients at follow-up (p = 0.0001 vs. first visit). Left ventricular ejection fraction did not differ between patients and controls at baseline and at follow-up. CONCLUSION: We could identify a significantly higher global STIR+ ratio in patients with suspected myocarditis compared to controls, and a dynamic change during follow-up. The global STIR+ ratio may, therefore, be useful for the diagnosis of myocarditis and should be further explored.

Authors with CRIS profile

Stephan Achenbach Department of Medicine 2 – Cardiology and Angiology

Involved external institutions

Semmelweis University / Semmelweis Egyetem HU Hungary (HU) Albert-Ludwigs-Universität Freiburg DE Germany (DE) University of Physical Education HU Hungary (HU)

How to cite

APA:

Jeserich, M., Merkely, B., Schlosser, P., Kimmel, S., Pavlik, G., & Achenbach, S. (2017). Assessment of edema using STIR+ via 3D cardiovascular magnetic resonance imaging in patients with suspected myocarditis. Magnetic Resonance Materials in Physics Biology and Medicine, 30(3), 309-316. https://doi.org/10.1007/s10334-016-0603-y

MLA:

Jeserich, Michael, et al. "Assessment of edema using STIR+ via 3D cardiovascular magnetic resonance imaging in patients with suspected myocarditis." Magnetic Resonance Materials in Physics Biology and Medicine 30.3 (2017): 309-316.

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