Promoting access to innovation for frail old persons

Berrut G, Andrieu S, De Carvalho IA, Baeyens JP, Bergman H, Cassim B, Cerreta F, Cesari M, Cha HB, Chen LK, Cherubini A, Chou MY, Cruz-Jentoft AJ, De Decker L, Du P, Forette B, Forette F, Franco A, Guimaraes R, Gutierrez-Robledo LM, Jauregui J, Khavinson V, Lee WJ, Peng LN, Perret-Guillaume C, Petrovic M, Retornaz F, Rockwood K, Rodriguez-Manas L, Sieber C, Spatharakis G, Theou O, Topinkova E, Vellas B, Benetos A (2013)

Publication Status: Published

Publication Type: Journal article

Publication year: 2013

Journal

Publisher: SPRINGER FRANCE

Book Volume: 17

Pages Range: 688-693

Journal Issue: 8

DOI: 10.1007/s12603-013-0039-2

Abstract

Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate.The purpose of this paper is to present expert's positions on the main aspects of the frailty syndrome in the older persons.Workshop organized by International Association of Gerontology and Geriatrics (IAGG), World Health Organization (WHO) and Soci,t, Fran double dagger aise de G,riatrie et de G,rontologie (SFGG).Frailty is widely recognized as an important risk factor for adverse health outcomes in older persons. This can be of particular value in evaluating non-disabled older persons with chronic diseases but today no operational definition has been established. Nutritional status, mobility, activity, strength, endurance, cognition, and mood have been proposed as markers of frailty. Another approach calculates a multidimensional score ranging from "very fit" to "severely frail," but it is difficult to apply into the medical practice. Frailty appears to be secondary to multiple conditions using multiple pathways leading to a vulnerability to a stressor. Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.), as well as social factors (isolation, financial situation) are involved in the vulnerability process. In clinical practice, detection of frailty is of major interest in oncology because of the high prevalence of cancer in older persons and the bad tolerance of the drug therapies. Presence of frailty should also be taken into account in the definition of the cardiovascular risks in the older population. The experts of the workshop have listed the points reached an agreement and those must to be a priority for improving understanding and use of frailty syndrome in practice.Frailty in older adults is a syndrome corresponding to a vulnerability to a stressor. Diagnostic tools have been developed but none can integrate at the same time the large spectrum of factors and the simplicity asked by the clinical practice. An agreement with an international common definition is necessary to develop screening and to reduce the morbidity in older persons.

Authors with CRIS profile

Involved external institutions

European Medicines Agency United Kingdom (GB) Nantes University Hospital / Centre hospitalier universitaire de Nantes (CHU) France (FR) Taipei Veterans General Hospital / 台北榮民總醫院 Taiwan (TW) Hospital Italiano de Buenos Aires Argentina (AR) World Health Organization Switzerland (CH) Hospital Universitario Ramón y Cajal Spain (ES) McGill University Canada (CA) St. Petersburg Institute of Bioregulation and Gerontology Russian Federation (RU) Centre Hospitalier Universitaire (CHU) de Toulouse France (FR) Hôpital Sainte-Périne / Sainte-Perine Hospital France (FR) Hallym University Korea, Republic of (KR) Az Damiaan Belgium (BE) Hôpital l'Archet (CHU de Nice) France (FR) Renmin University of China China (CN) Istituto Nazionale di Riposo e Cura per Anziani (IRCCS INRCA) Italy (IT) Instituto Nacional de Geriatría Mexico (MX) Kaohsiung Veterans General Hospital Taiwan (TW) Hospital Universitario de Getafe Spain (ES) Centre Gérontologique Départemental de Marseille France (FR) Univerzita Karlova v Praze / Charles University in Prague Czech Republic (CZ) Dalhousie University Canada (CA) University Hospital Ghent Belgium (BE) Centre Hospitalier Universitaire de Nancy / CHU Hôpitaux de Brabois France (FR) National Institute for Health and Medical Research / Institut national de la santé et de la recherche médicale (INSERM) France (FR)

How to cite

APA:

Berrut, G., Andrieu, S., De Carvalho, I.A., Baeyens, J.P., Bergman, H., Cassim, B.,... Benetos, A. (2013). Promoting access to innovation for frail old persons. Journal of Nutrition, Health & Aging, 17(8), 688-693. https://dx.doi.org/10.1007/s12603-013-0039-2

MLA:

Berrut, G., et al. "Promoting access to innovation for frail old persons." Journal of Nutrition, Health & Aging 17.8 (2013): 688-693.

BibTeX: Download