Patients' and Physicians' Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)

Schaarschmidt ML, Herr RM, Gutknecht M, Wroblewska K, Gerdes S, Sticherling M, Augustin M, Peitsch WK (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Acta Dermato-Venereologica Society for Publication of Acta Dermato-Venereologica

Book Volume: 98

Pages Range: 200-205

Journal Issue: 2

DOI: 10.2340/00015555-2834

Abstract

Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients' (n = 222) and physicians' (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using Relative Importance Scores (RIS). Both groups considered Psoriasis Area and Severity Index 90 (PASI 90) to be most important (RIS 21.4 and 20.8, respectively). Moreover, patients were highly concerned about mild and severe adverse events (RIS = 18.2 and 14.2), physicians about severe adverse events (RIS = 14.9) and cost (RIS = 13.8). Compared to physicians, patients worried more about mild adverse events and treatment location, but less about cost and frequency of laboratory tests. Physicians' preferences were influenced by work experience and percentage of biological prescriptions, patients' preferences by age, disease duration and severity. Older and less severely affected patients recruited via a patient organization focused more on safety, but less on efficacy and time until response than did patients from study centres. In conclusion, these differences in trade-offs should be integrated into a shared decision-making.

Authors with CRIS profile

Raphael Herr
Michael Sticherling Professur für Dermatologie

Involved external institutions

Universitätsklinikum Mannheim DE Germany (DE) Universitätsklinikum Hamburg-Eppendorf (UKE) DE Germany (DE) Hautarztpraxis Dr. Wroblewska DE Germany (DE) Universitätsklinikum Schleswig-Holstein (UKSH) DE Germany (DE) Ruprecht-Karls-Universität Heidelberg DE Germany (DE)

How to cite

APA:

Schaarschmidt, M.-L., Herr, R.M., Gutknecht, M., Wroblewska, K., Gerdes, S., Sticherling, M.,... Peitsch, W.K. (2018). Patients' and Physicians' Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare). Acta Dermato-Venereologica, 98(2), 200-205. https://dx.doi.org/10.2340/00015555-2834

MLA:

Schaarschmidt, Marthe-Lisa, et al. "Patients' and Physicians' Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)." Acta Dermato-Venereologica 98.2 (2018): 200-205.

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