Puisieux A, Brabletz T, Caramel J (2014)
Publication Type: Journal article
Publication year: 2014
Publisher: Nature Publishing Group
Book Volume: 16
Pages Range: 488-94
Journal Issue: 6
DOI: 10.1038/ncb2976
The plasticity of cancer cells underlies their capacity to adapt to the selective pressures they encounter during tumour development. Aberrant reactivation of epithelial-mesenchymal transition (EMT), an essential embryonic process, can promote cancer cell plasticity and fuel both tumour initiation and metastatic spread. Here we discuss the roles of EMT-inducing transcription factors in creating a pro-tumorigenic setting characterized by an intrinsic ability to withstand oncogenic insults through the mitigation of p53-dependent oncosuppressive functions and the gain of stemness-related properties.
APA:
Puisieux, A., Brabletz, T., & Caramel, J. (2014). Oncogenic roles of EMT-inducing transcription factors. Nature Cell Biology, 16(6), 488-94. https://doi.org/10.1038/ncb2976
MLA:
Puisieux, Alain, Thomas Brabletz, and Julie Caramel. "Oncogenic roles of EMT-inducing transcription factors." Nature Cell Biology 16.6 (2014): 488-94.
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