Perioperative complications of scoliosis surgery in patients with Duchenne muscular dystrophy and spinal muscular atrophy, focussing on wound healing disorders

Journal article


Publication Details

Author(s): Burow M, Forst R, Forst J, Hofner B, Fujak A
Journal: International Journal of Neuroscience
Publication year: 2017
Volume: 127
Journal issue: 6
Pages range: 479-485
ISSN: 0020-7454


Abstract


Patients with Duchenne muscular dystrophy (DMD) or spinal muscular atrophy (SMA), both neuromuscular diseases, sustain spinal scoliosis in the course of their disease. To reduce the concomitant major morbidity and to improve their quality of life, patients require surgical spine stabilization. This can lead to complications like respiratory, cardiac or neurological complications or wound healing disorders (WHD). To find out the different complexities and risk factors increasing the chance to develop a WHD, the inpatient database was analyzed.We performed a retrospective statistical study. Therefore, we analyzed the inpatient database of 180 patients (142 DMD and 38 SMA patients). The focus was on WHD. To figure out the risk factors leading to WHD, we conducted a logistic regression.Cardiac complications occurred most frequently, followed by pulmonary complications and neurological lesions. Fifty-seven out of 180 patients developed a WHD. In 23 cases the WHD was aseptic, in the other 34 cases dermal organisms, Pseudomonas species and intestinal organisms were responsible. By means of the logistic regression, we were able to identify two more risk factors, in addition to diagnosis and gender, for developing a WHD in our patients: the year of surgery and the direction of pelvic tilt.Most common complications following scoliosis surgery are respiratory and cardiac complications. WHD is a severe complication that implies a prolonged therapy. Some risk factors for developing WHD could be identified in this analysis. Specifically, these were the date of surgery and the direction of pelvic tilt.



FAU Authors / FAU Editors

Burow, Mareike
Lehrstuhl für Orthopädie mit Orthopädischer Chirurgie
Forst, Raimund Prof. Dr. med.
Lehrstuhl für Orthopädie mit Orthopädischer Chirurgie
Forst, Jürgen Prof. Dr.
Medizinische Fakultät
Hofner, Benjamin PD Dr.
Lehrstuhl für Biometrie und Epidemiologie


How to cite

APA:
Burow, M., Forst, R., Forst, J., Hofner, B., & Fujak, A. (2017). Perioperative complications of scoliosis surgery in patients with Duchenne muscular dystrophy and spinal muscular atrophy, focussing on wound healing disorders. International Journal of Neuroscience, 127(6), 479-485. https://dx.doi.org/10.1080/00207454.2016.1196688

MLA:
Burow, Mareike, et al. "Perioperative complications of scoliosis surgery in patients with Duchenne muscular dystrophy and spinal muscular atrophy, focussing on wound healing disorders." International Journal of Neuroscience 127.6 (2017): 479-485.

BibTeX: 

Last updated on 2019-21-07 at 07:58