Strongly Directing Substituents in the Radical Arylation of Substituted Benzenes

Hofmann J, Clark T, Heinrich M (2016)

Publication Language: English

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2016

Journal

Journal of Organic Chemistry American Chemical Society

Publisher: American Chemical Society

Book Volume: 81

Pages Range: 9785-9791

Journal Issue: 20

DOI: 10.1021/acs.joc.6b01840

Abstract

Although general interest in radical arylation reactions has grown rapidly in recent years, poor regioselectivities and the need to use a large excess of the radical-accepting arene have hindered their application to substituted benzenes. We now describe experimental and computational investigations into the substituent effects that lead to regioselective addition based on the recent discovery of anilines as outstanding substrates for radical arylations.

Authors with CRIS profile

Josefa Hofmann Professur für Pharmazeutische Chemie Timothy Clark Computer-Chemie-Centrum Markus Heinrich Professur für Pharmazeutische Chemie

How to cite

APA:

Hofmann, J., Clark, T., & Heinrich, M. (2016). Strongly Directing Substituents in the Radical Arylation of Substituted Benzenes. Journal of Organic Chemistry, 81(20), 9785-9791. https://dx.doi.org/10.1021/acs.joc.6b01840

MLA:

Hofmann, Josefa, Timothy Clark, and Markus Heinrich. "Strongly Directing Substituents in the Radical Arylation of Substituted Benzenes." Journal of Organic Chemistry 81.20 (2016): 9785-9791.

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