CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication
Dettmer J, Ursache R, Campilho A, Miyashima S, Belevich I, O'Regan S, Mullendore DL, Yadav SR, Lanz C, Beverina L, Papagni A, Schneeberger K, Weigel D, Stierhof YD, Moritz T, Knoblauch M, Jokitalo E, Helariutta Y (2014)
Publication Status: Published
Publication Type: Journal article
Publication year: 2014
Journal
Publisher: Nature Publishing Group: Nature Communications
Book Volume: 5
DOI: 10.1038/ncomms5276
Abstract
Phloem, a plant tissue responsible for long-distance molecular transport, harbours specific junctions, sieve areas, between the conducting cells. To date, little is known about the molecular framework related to the biogenesis of these sieve areas. Here we identify mutations at the CHER1/AtCTL1 locus of Arabidopsis thaliana. The mutations cause several phenotypic abnormalities, including reduced pore density and altered pore structure in the sieve areas associated with impaired phloem function. CHER1 encodes a member of a poorly characterized choline transporter-like protein family in plants and animals. We show that CHER1 facilitates choline transport, localizes to the trans-Golgi network, and during cytokinesis is associated with the phragmoplast. Consistent with its function in the elaboration of the sieve areas, CHER1 has a sustained, polar localization in the forming sieve plates. Our results indicate that the regulation of choline levels is crucial for phloem development and conductivity in plants.
Authors with CRIS profile
Involved external institutions
Helsingin yliopisto / University of Helsinki
Finland (FI)
Washington State University (WSU)
United States (USA) (US)
Swedish University of Agricultural Sciences / Sveriges Lantbruksuniversitet (SLU)
Sweden (SE)
Eberhard Karls Universität Tübingen
Germany (DE)
Max-Planck-Institut für Entwicklungsbiologie / Max Planck Institute for Developmental Biology
Germany (DE)
Max-Planck-Institut für Pflanzenzüchtungsforschung / Max Planck Institute for Plant Breeding Research
Germany (DE)
University of Milano-Bicocca / Università degli Studi di Milano-Bicocca, UNIMIB
Italy (IT)
University of Paris 5 - René Descartes / Université Paris V René Descartes
France (FR)
Universidade do Porto
Portugal (PT)
Finland (FI)
Washington State University (WSU)
United States (USA) (US)
Swedish University of Agricultural Sciences / Sveriges Lantbruksuniversitet (SLU)
Sweden (SE)
Eberhard Karls Universität Tübingen
Germany (DE)
Max-Planck-Institut für Entwicklungsbiologie / Max Planck Institute for Developmental Biology
Germany (DE)
Max-Planck-Institut für Pflanzenzüchtungsforschung / Max Planck Institute for Plant Breeding Research
Germany (DE)
University of Milano-Bicocca / Università degli Studi di Milano-Bicocca, UNIMIB
Italy (IT)
University of Paris 5 - René Descartes / Université Paris V René Descartes
France (FR)
Universidade do Porto
Portugal (PT)
How to cite
APA:
Dettmer, J., Ursache, R., Campilho, A., Miyashima, S., Belevich, I., O'Regan, S.,... Helariutta, Y. (2014). CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication. Nature Communications, 5. https://dx.doi.org/10.1038/ncomms5276
MLA:
Dettmer, Jan, et al. "CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication." Nature Communications 5 (2014).
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