OARSI Clinical Trials Recommendations: Hand imaging in clinical trials in osteoarthritis

Hunter DJ, Arden N, Cicuttini FM, Crema MD, Dardzinski B, Duryea J, Guermazi A, Haugen IK, Kloppenburg M, Maheu E, Miller CG, Martel-Pelletier J, Ochoa-Albiztegui RE, Pelletier JP, Peterfy C, Roemer F, Gold GE (2015)

Publication Type: Journal article, Review article

Publication year: 2015

Journal

Osteoarthritis and Cartilage Elsevier

Book Volume: 23

Pages Range: 732-46

Journal Issue: 5

DOI: 10.1016/j.joca.2015.03.003

Abstract

Tremendous advances have occurred in our understanding of the pathogenesis of hand osteoarthritis (OA) and these are beginning to be applied to trials targeted at modification of the disease course. The purpose of this expert opinion, consensus driven exercise is to provide detail on how one might use and apply hand imaging assessments in disease modifying clinical trials. It includes information on acquisition methods/techniques (including guidance on positioning for radiography, sequence/protocol recommendations/hardware for MRI); commonly encountered problems (including positioning, hardware and coil failures, sequences artifacts); quality assurance/control procedures; measurement methods; measurement performance (reliability, responsiveness, validity); recommendations for trials; and research recommendations.

Authors with CRIS profile

Frank Roemer Institute of Radiology

Involved external institutions

University of Sydney (USYD) AU Australia (AU) University of Oxford GB United Kingdom (GB) Monash University AU Australia (AU) Boston University US United States (USA) (US) Uniformed Services University US United States (USA) (US) Harvard University US United States (USA) (US) Diakonhjemmet Hospital NO Norway (NO) Leiden University NL Netherlands (NL) Hôpital Saint-Antoine FR France (FR) BioClinica US United States (USA) (US) Centre de recherche du C.H.U.M. CA Canada (CA) American British Cowdray (ABC) Medical Center MX Mexico (MX) Spire Sciences LLC US United States (USA) (US) Stanford University US United States (USA) (US)

How to cite

APA:

Hunter, D.J., Arden, N., Cicuttini, F.M., Crema, M.D., Dardzinski, B., Duryea, J.,... Gold, G.E. (2015). OARSI Clinical Trials Recommendations: Hand imaging in clinical trials in osteoarthritis. Osteoarthritis and Cartilage, 23(5), 732-46. https://dx.doi.org/10.1016/j.joca.2015.03.003

MLA:

Hunter, D. J., et al. "OARSI Clinical Trials Recommendations: Hand imaging in clinical trials in osteoarthritis." Osteoarthritis and Cartilage 23.5 (2015): 732-46.

BibTeX: Download