Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF exchange factors

Journal article


Publication Details

Author(s): Richter S, Mueller LM, Stierhof YD, Mayer U, Takada N, Kost B, Vieten A, Geldner N, Koncz C, Juergens G
Journal: Nature Cell Biology
Publisher: Nature Publishing Group
Publication year: 2012
Volume: 14
Journal issue: 1
Pages range: 80-U130
ISSN: 1465-7392


Abstract


Polarized tip growth is a fundamental cellular process in many eukaryotic organisms, mediating growth of neuronal axons and dendrites(1) or fungal hyphae(2). In plants, pollen and root hairs are cellular model systems for analysing tip growth(3-5). Cell growth depends on membrane traffic. The regulation of this membrane traffic is largely unknown for tip-growing cells, in contrast to cells exhibiting intercalary growth. Here we show that in Arabidopsis, GBF1-related exchange factors for the ARF GTPases (ARF GEFs) GNOM and GNL2 play essential roles in polar tip growth of root hairs and pollen, respectively. When expressed from the same promoter, GNL2 (incontrast to the early-secretory ARF GEF GNL1) is able to replace GNOM in polar recycling of the auxin efflux regulator PIN1 from endosomes to the basal plasma membrane in non-tip growing cells. Thus, polar recycling facilitates polar tip growth, and GNL2 seems to have evolved to meet the specific requirement of fast-growing pollen in higher plants.



FAU Authors / FAU Editors

Kost, Benedikt Prof. Dr.
Lehrstuhl für Zellbiologie


How to cite

APA:
Richter, S., Mueller, L.M., Stierhof, Y.-D., Mayer, U., Takada, N., Kost, B.,... Juergens, G. (2012). Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF exchange factors. Nature Cell Biology, 14(1), 80-U130. https://dx.doi.org/10.1038/ncb2389

MLA:
Richter, Sandra, et al. "Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF exchange factors." Nature Cell Biology 14.1 (2012): 80-U130.

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Last updated on 2018-19-04 at 03:40