Lesional cerebellar epilepsy: a review of the evidence

Foit NA, Van Velthoven V, Schulz R, Blümcke I, Urbach H, Woermann FG, Bien CG (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Journal of Neurology Springer Verlag (Germany)

Book Volume: 264

Pages Range: 1-10

Journal Issue: 1

DOI: 10.1007/s00415-016-8161-9

Abstract

Classical teaching in epileptology localizes the origins of focal seizures solely in the cerebral cortex, with only inhibitory effects attributed to subcortical structures. However, electrophysiological and neuroimaging studies over the last decades now provide evidence for an initiation of epileptic seizures within subcortical structures. Intrinsic epileptogenicity of hypothalamic hamartoma has already been established in recognition of subcortical epilepsy, whereas a seizure-generating impact of dysplastic cerebellar lesions remains to be clarified. Herein, we examine the supportive evidence and clinical presentation of cerebellar seizures and review therapy options.

Authors with CRIS profile

Ingmar Blümcke Lehrstuhl für Neuropathologie

Involved external institutions

Krankenhaus Mara DE Germany (DE) Universitätsklinikum Freiburg DE Germany (DE)

How to cite

APA:

Foit, N.A., Van Velthoven, V., Schulz, R., Blümcke, I., Urbach, H., Woermann, F.G., & Bien, C.G. (2017). Lesional cerebellar epilepsy: a review of the evidence. Journal of Neurology, 264(1), 1-10. https://dx.doi.org/10.1007/s00415-016-8161-9

MLA:

Foit, Niels A., et al. "Lesional cerebellar epilepsy: a review of the evidence." Journal of Neurology 264.1 (2017): 1-10.

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