Identification of interaction partners of ?-thymosins: application of thymosin ?4 labeled by transglutaminase
App C, Knop J, Mannherz HG, Hannappel E (2012)
Publication Type: Journal article
Publication year: 2012
Journal
Publisher: New York Academy of Sciences
Book Volume: 1270
Pages Range: 98-104
DOI: 10.1111/j.1749-6632.2012.06658.x
Abstract
In this review, we identify potential interaction partners of the ?-thymosin family. The proteins of this family are highly conserved peptides in mammals and yet only one intracellular (G-actin) and one cell-surface protein (? subunit of F(1) -F(0) ATP synthase) were identified as interaction partners of thymosin ?4. Cross-linking experiments may be a possible approach to discover additional proteins that interact with the ?-thymosin family. It has previously been shown that thymosin ?4 can be labeled at its glutaminyl residues with various cadaverines using tissue transglutaminase. Here, we illuminate recent results and give an outlook on upcoming work in the field.
Authors with CRIS profile
Christine App
Lehrstuhl für Biochemie und Pathobiochemie
Jana Knop
Lehrstuhl für Biochemie und Pathobiochemie
Ewald Hannappel
Professur für Biochemie und Molekulare Neurowissenschaften
Involved external institutions
Germany (DE)How to cite
APA:
App, C., Knop, J., Mannherz, H.G., & Hannappel, E. (2012). Identification of interaction partners of ?-thymosins: application of thymosin ?4 labeled by transglutaminase. Annals of the New York Academy of Sciences, 1270, 98-104. https://dx.doi.org/10.1111/j.1749-6632.2012.06658.x
MLA:
App, Christine, et al. "Identification of interaction partners of ?-thymosins: application of thymosin ?4 labeled by transglutaminase." Annals of the New York Academy of Sciences 1270 (2012): 98-104.
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