Albumin coatings by alternating current electrophoretic deposition for improving corrosion resistance and bioactivity of titanium implants
Höhn S, Braem A, Neirinck B, Virtanen S (2017)
Publication Language: English
Publication Type: Journal article
Publication year: 2017
Journal
Pages Range: 798-807
Journal Issue: 73
DOI: 10.1016/j.msec.2016.12.129
Abstract
Although Ti alloys are generally regarded to be highly corrosion resistant, inflammatory conditions following surgery can instigate breakdown of the TiO2 passivation layer leading to an increased metal ion release. Furthermore proteins present in the surrounding tissue will readily adsorb on a titanium surface after implantation. In this paper alternating current electrophoretic deposition (AC-EPD) of bovine serum albumin (BSA) on Ti6Al4V was investigated in order to increase the corrosion resistance and control the protein adsorption capability of the implant
surface. The Ti6Al4V surface was characterized with SEM, XPS and ToF-SIMS after long-term immersion tests under physiological conditions and simulated inflammatory conditions either in Dulbecco's Modified Eagle Medium (DMEM) or DMEM supplemented with fetal calf serum (FCS). The analysis showed an increased adsorption of amino acids and proteins from the different immersion solutions. The BSA coating was shown to prevent selective dissolution of the vanadium (V) rich β-phase, thus effectively limiting metal ion release to the environment. Electrochemical impedance spectroscopy measurements confirmed an increase of the corrosion
resistance for BSA coated surfaces as a function of immersion time due to the time-dependent adsorption of the different amino acids (from DMEM) and proteins (from FCS) as observed by ToF-SIMS analysis.
Authors with CRIS profile
Sarah Höhn
Professur für Werkstoffwissenschaften (Korrosion und Oberflächentechnik)
Sannakaisa Virtanen
Professur für Werkstoffwissenschaften (Korrosion und Oberflächentechnik)
Involved external institutions
Belgium (BE)How to cite
APA:
Höhn, S., Braem, A., Neirinck, B., & Virtanen, S. (2017). Albumin coatings by alternating current electrophoretic deposition for improving corrosion resistance and bioactivity of titanium implants. Materials Science and Engineering C, 73, 798-807. https://dx.doi.org/10.1016/j.msec.2016.12.129
MLA:
Höhn, Sarah, et al. "Albumin coatings by alternating current electrophoretic deposition for improving corrosion resistance and bioactivity of titanium implants." Materials Science and Engineering C 73 (2017): 798-807.
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