Spectra library: An assumption-free in situ method to access the kinetics of catechols binding to colloidal ZnO quantum dots

Beitrag in einer Fachzeitschrift
(Originalarbeit)


Details zur Publikation

Autorinnen und Autoren: Lin W, Haderlein M, Walter J, Peukert W, Segets D
Zeitschrift: Angewandte Chemie International Edition
Verlag: Wiley-VCH Verlag
Jahr der Veröffentlichung: 2016
Band: 55
Heftnummer: 3
Seitenbereich: 932-935
ISSN: 1433-7851
eISSN: 1521-3773


Abstract


Assumption-free and in situ resolving of the kinetics of ligand binding to colloidal nanoparticles (NPs) with high time resolution is still a challenge in NP research. A unique concept of using spectra library and stopped-flow together with a "search best-match" Matlab algorithm to access the kinetics of ligand binding in colloidal systems is reported. Instead of deconvoluting superimposed spectra using assumptions, species absorbance contributions (ligand@ZnO NPs and ligand in solution) are obtained by offline experiments. Therefrom, a library of well-defined targets with known ligand distribution between particle surface and solution is created. Finally, the evolution of bound ligand is derived by comparing in situ spectra recorded by stopped-flow and the library spectra with the algorithm. Our concept is a widely applicable strategy for kinetic studies of ligand adsorption to colloidal NPs and a big step towards deep understanding of surface functionalization kinetics. Well-established libraries of target spectra that are derived by means of careful offline analysis and identification of equilibrium data within larger kinetic datasets can be used for any particle-ligand system. Kinetics of ligand binding to nanoparticles can be derived free of assumption, in situ, and with high time resolution.



FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Haderlein, Michael
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik
Lin, Wei
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik
Peukert, Wolfgang Prof. Dr.-Ing.
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik
Segets, Doris Dr.-Ing.
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik
Walter, Johannes Dr.-Ing.
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik


Zusätzliche Organisationseinheit(en)
Exzellenz-Cluster Engineering of Advanced Materials


Forschungsbereiche

A1 Functional Particle Systems
Exzellenz-Cluster Engineering of Advanced Materials


Zitierweisen

APA:
Lin, W., Haderlein, M., Walter, J., Peukert, W., & Segets, D. (2016). Spectra library: An assumption-free in situ method to access the kinetics of catechols binding to colloidal ZnO quantum dots. Angewandte Chemie International Edition, 55(3), 932-935. https://dx.doi.org/10.1002/anie.201508252

MLA:
Lin, Wei, et al. "Spectra library: An assumption-free in situ method to access the kinetics of catechols binding to colloidal ZnO quantum dots." Angewandte Chemie International Edition 55.3 (2016): 932-935.

BibTeX: 

Zuletzt aktualisiert 2019-13-03 um 10:53