A family of hyperelastic models for human brain tissue

Journal article
(Original article)


Publication Details

Author(s): Mihai LA, Budday S, Holzapfel GA, Kuhl E, Goriely A
Journal: Journal of the Mechanics and Physics of Solids
Publication year: 2017
Volume: 106
Pages range: 60-79
ISSN: 0022-5096
Language: English


Abstract


Experiments on brain samples under multiaxial loading have shown that human brain tissue is both extremely soft when compared to other biological tissues and characterized by a peculiar elastic response under combined shear and compression/tension: there is a significant increase in shear stress with increasing axial compression compared to a moderate increase with increasing axial tension. Recent studies have revealed that many widely used constitutive models for soft biological tissues fail to capture this characteristic response. Here, guided by experiments of human brain tissue, we develop a family of modeling approaches that capture the elasticity of brain tissue under varying simple shear superposed on varying axial stretch by exploiting key observations about the behavior of the nonlinear shear modulus, which can be obtained directly from the experimental data.



FAU Authors / FAU Editors

Budday, Silvia Dr.-Ing.
Lehrstuhl für Technische Mechanik


External institutions with authors

Cardiff University
Stanford University
Technische Universität Graz
University of Oxford


How to cite

APA:
Mihai, L.A., Budday, S., Holzapfel, G.A., Kuhl, E., & Goriely, A. (2017). A family of hyperelastic models for human brain tissue. Journal of the Mechanics and Physics of Solids, 106, 60-79. https://dx.doi.org/10.1016/j.jmps.2017.05.015

MLA:
Mihai, L. Angela, et al. "A family of hyperelastic models for human brain tissue." Journal of the Mechanics and Physics of Solids 106 (2017): 60-79.

BibTeX: 

Last updated on 2018-17-10 at 11:00