Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS): prospects for a feedback mechanism for surgical laser systems

Journal article
(Online publication)


Publication Details

Author(s): Kanawade R, Mehari FA, Klämpfl F, Rohde M, Knipfer C, Tangermann-Gerk K, Adler W, Schmidt M, Stelzle F
Journal: Journal of Biophotonics
Publisher: Wiley-VCH Verlag
Publication year: 2013
Volume: 8
Journal issue: 1-2
Pages range: 153-61
ISSN: 1864-063X
Language: English


Abstract


The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. Ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experiment. Atomic emission intensity ratios were analyzed to find a characteristic spectral line for each tissue. The results showed characteristic elemental emission intensity ratios for the respective tissues. The spectral lines and intensity ratios of these specific elements varied among the different tissue types. The main goal of this study is to qualitatively and precisely identify different tissue types for tissue specific laser surgery. (© 2013 WILEY-VCH Verlag GmbH &Co. KGaA, Weinheim).



FAU Authors / FAU Editors

Adler, Werner PD Dr.
Lehrstuhl für Biometrie und Epidemiologie
Kanawade, Rajesh
Lehrstuhl für Photonische Technologien
Klämpfl, Florian Dr.-Ing.
Lehrstuhl für Photonische Technologien
Mehari, Fanuel Andemariam
Lehrstuhl für Photonische Technologien
Schmidt, Michael Prof. Dr.-Ing.
Lehrstuhl für Photonische Technologien
Stelzle, Florian Prof. Dr. Dr.
Medizinische Fakultät


Additional Organisation
Erlangen Graduate School in Advanced Optical Technologies


How to cite

APA:
Kanawade, R., Mehari, F.A., Klämpfl, F., Rohde, M., Knipfer, C., Tangermann-Gerk, K.,... Stelzle, F. (2013). Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS): prospects for a feedback mechanism for surgical laser systems. Journal of Biophotonics, 8(1-2), 153-61. https://dx.doi.org/10.1002/jbio.201300159

MLA:
Kanawade, Rajesh, et al. "Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS): prospects for a feedback mechanism for surgical laser systems." Journal of Biophotonics 8.1-2 (2013): 153-61.

BibTeX: 

Last updated on 2018-19-04 at 03:02