Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles

Journal article


Publication Details

Author(s): Lyer S, Tietze R, Unterweger H, Zaloga J, Singh R, Matuszak J, Poettler M, Friedrich RP, Dürr S, Cicha I, Janko C, Alexiou C
Journal: Nanomedicine
Publication year: 2015
Volume: 10
Journal issue: 21
Pages range: 3287-304
ISSN: 1743-5889


Abstract


Nanomedicine offers tremendous opportunities for the development of novel therapeutic and diagnostic tools. During the last decades, extensive knowledge was gained about stabilizing and the coating of nanoparticles, their functionalization for drug binding and drug release and possible strategies for therapies and diagnostics of different diseases. Most recently, more and more emphasis has been placed on nanotoxicology and nanosafety aspects. The section of experimental oncology and nanomedicine developed a concept for translating this knowledge into clinical application of magnetic drug targeting for the treatment of cancer and other diseases using superparamagnetic iron oxide nanoparticles. This approach includes reproducible synthesis, detailed characterization, nanotoxicological testing, evaluation in ex vivo models, preclinical animal studies and production of superparamagnetic iron oxide nanoparticles according to good manufacturing practice regulations.



FAU Authors / FAU Editors

Alexiou, Christoph Prof. Dr.
Professur für Nanomedizin
Janko, Christina Dr. rer. nat.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Lyer, Stefan Dr. rer. nat.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Matuszak, Jasmin
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Tietze, Rainer Dr. rer. nat.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Unterweger, Harald Dr.-Ing.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Zaloga, Jan Dr. rer. nat.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie


How to cite

APA:
Lyer, S., Tietze, R., Unterweger, H., Zaloga, J., Singh, R., Matuszak, J.,... Alexiou, C. (2015). Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles. Nanomedicine, 10(21), 3287-304. https://dx.doi.org/10.2217/nnm.15.159

MLA:
Lyer, Stefan, et al. "Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles." Nanomedicine 10.21 (2015): 3287-304.

BibTeX: 

Last updated on 2018-09-10 at 07:19