Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles

Lyer S, Tietze R, Unterweger H, Zaloga J, Singh R, Matuszak J, Poettler M, Friedrich RP, Dürr S, Cicha I, Janko C, Alexiou C (2015)


Publication Type: Journal article

Publication year: 2015

Journal

Book Volume: 10

Pages Range: 3287-304

Journal Issue: 21

DOI: 10.2217/nnm.15.159

Abstract

Nanomedicine offers tremendous opportunities for the development of novel therapeutic and diagnostic tools. During the last decades, extensive knowledge was gained about stabilizing and the coating of nanoparticles, their functionalization for drug binding and drug release and possible strategies for therapies and diagnostics of different diseases. Most recently, more and more emphasis has been placed on nanotoxicology and nanosafety aspects. The section of experimental oncology and nanomedicine developed a concept for translating this knowledge into clinical application of magnetic drug targeting for the treatment of cancer and other diseases using superparamagnetic iron oxide nanoparticles. This approach includes reproducible synthesis, detailed characterization, nanotoxicological testing, evaluation in ex vivo models, preclinical animal studies and production of superparamagnetic iron oxide nanoparticles according to good manufacturing practice regulations.

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How to cite

APA:

Lyer, S., Tietze, R., Unterweger, H., Zaloga, J., Singh, R., Matuszak, J.,... Alexiou, C. (2015). Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles. Nanomedicine, 10(21), 3287-304. https://dx.doi.org/10.2217/nnm.15.159

MLA:

Lyer, Stefan, et al. "Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles." Nanomedicine 10.21 (2015): 3287-304.

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