Boron containing magnetic nanoparticles for neutron capture therapy - an innovative approach for specifically targeting tumors

Journal article


Publication Details

Author(s): Tietze R, Unterweger H, Dürr S, Lyer S, Canella L, Kudejova P, Wagner FM, Petry W, Taccardi N, Alexiou C
Journal: Applied Radiation and Isotopes
Publisher: Elsevier
Publication year: 2015
Volume: 106
Pages range: 151-5
ISSN: 0969-8043


Abstract

The selective delivery of (10)B into the tumor tissue remains to be further improved for successful and reliable Boron Neutron Capture Therapy applications. Magnetic Drug Targeting using intraarterially administered superparamagnetic nanoparticles and external magnetic fields already exhibited convincing results in terms of highly efficient and selective drug deposition. Using the same technique for the targeted (10)B delivery is a promising new approach. Here, systematic irradiation experiments of phantom cubes containing different concentrations of boron and nanoparticles as well as varying three-dimensional arrangements have been performed.


FAU Authors / FAU Editors

Alexiou, Christoph Prof. Dr.
Professur für Nanomedizin
Lyer, Stefan Dr. rer. nat.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Taccardi, Nicola Dr.
Lehrstuhl für Chemische Reaktionstechnik
Unterweger, Harald Dr.-Ing.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie


Additional Organisation
Exzellenz-Cluster Engineering of Advanced Materials


External institutions with authors

Technische Universität München (TUM)


Research Fields

D Catalytic Materials
Exzellenz-Cluster Engineering of Advanced Materials
Nanosafety
Exzellenz-Cluster Engineering of Advanced Materials


How to cite

APA:
Tietze, R., Unterweger, H., Dürr, S., Lyer, S., Canella, L., Kudejova, P.,... Alexiou, C. (2015). Boron containing magnetic nanoparticles for neutron capture therapy - an innovative approach for specifically targeting tumors. Applied Radiation and Isotopes, 106, 151-5. https://dx.doi.org/10.1016/j.apradiso.2015.07.028

MLA:
Tietze, Rainer, et al. "Boron containing magnetic nanoparticles for neutron capture therapy - an innovative approach for specifically targeting tumors." Applied Radiation and Isotopes 106 (2015): 151-5.

BibTeX: 

Last updated on 2019-18-07 at 07:26