Differential diagnostic ultrasound criteria of papillary and follicular carcinomas: a multivariate analysis

Cordes M, Kondrat P, Uder M, Kuwert T, Sasiadek M (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren Georg Thieme Verlag

Book Volume: 186

Pages Range: 489-95

Journal Issue: 5

DOI: 10.1055/s-0034-1366282

Abstract

The purpose of the study was to test the hypothesis that papillary thyroid carcinomas (PTCs) and follicular thyroid carcinomas (FTCs) appear with different ultrasound characteristics.90 patients (70 females, 20 males) were included in the study in whom after thyroidectomy the diagnoses of PTCs or FTCs were established. 33 patients (25 females, 8 males) with the diagnosis of follicular adenoma were included in the study as controls (KONs). All patients had ultrasound examinations of the thyroid preoperatively. These ultrasound examinations were evaluated retrospectively with respect to the ultrasound characteristics: "size", "shape", "contour", "structure", "echogenicity" and "calcifications".In PTCs, FTCs and KONs "size" was significantly different (PTCs: MW = 12.5 mm, SD = 8. mm - FTCs: MW = 35.4 mm, SD = 19.6 mm - KONs: MW = 22.7 mm, SD = 14.5 mm; p < 0.001 for PTCs vs. FTCs, p < 0.001 for PTCs vs. KONs, p = 0.013 for FTCs vs. KONs). Differences were also found with respect to "contour" and "echogenicity" among PTCs, FTCs and KONs (p <= 0.035). The parameters "size", "contour", "echogenicity" and "calcifications" correlated for PTCs, FTCs and KONs with a correlation coefficient r = 0.57 (p < 0.05, multivariate regressionanalysis).PTCs and FTCs appear with different sonographic characteristics. Although there is some overlapping of the sonographic appearances of PTCs and FTCs, the knowledge of these differences should have some impact of the risk adapted further work up.

Authors with CRIS profile

Michael Uder Lehrstuhl für Diagnostische Radiologie Torsten Kuwert Lehrstuhl für Klinische Nuklearmedizin

Involved external institutions

Wrocław Medical University / Uniwersytet Medyczny we Wrocławiu PL Poland (PL) Radiologisch-Nuklearmedizinisches Zentrum DE Germany (DE)

How to cite

APA:

Cordes, M., Kondrat, P., Uder, M., Kuwert, T., & Sasiadek, M. (2014). Differential diagnostic ultrasound criteria of papillary and follicular carcinomas: a multivariate analysis. Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 186(5), 489-95. https://doi.org/10.1055/s-0034-1366282

MLA:

Cordes, M., et al. "Differential diagnostic ultrasound criteria of papillary and follicular carcinomas: a multivariate analysis." Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 186.5 (2014): 489-95.

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