EMT in cancer
Brabletz T, Kalluri R, Nieto MA, Weinberg RA (2018)
Publication Type: Journal article
Publication year: 2018
Journal
Book Volume: 18
Pages Range: 128-134
Journal Issue: 2
DOI: 10.1038/nrc.2017.118
Abstract
Similar to embryonic development, changes in cell phenotypes defined as an epithelial to mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process. Although the first description of EMT in cancer was in cell cultures, evidence for its role in vivo is now widely reported but also actively debated. Moreover, current research has exemplified just how complex this phenomenon is in cancer, leaving many exciting, open questions for researchers to answer in the future. With these points in mind, we asked four scientists for their opinions on the role of EMT in cancer and the challenges faced by scientists working in this fast-moving field.
Authors with CRIS profile
Thomas Brabletz
Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung
Involved external institutions
Massachusetts Institute of Technology (MIT)
United States (USA) (US)
Instituto de Neurociencias (IN)
Spain (ES)
University of Texas MD Anderson Cancer Center
United States (USA) (US)
United States (USA) (US)
Instituto de Neurociencias (IN)
Spain (ES)
University of Texas MD Anderson Cancer Center
United States (USA) (US)
How to cite
APA:
Brabletz, T., Kalluri, R., Nieto, M.A., & Weinberg, R.A. (2018). EMT in cancer. Nature Reviews Cancer, 18(2), 128-134. https://dx.doi.org/10.1038/nrc.2017.118
MLA:
Brabletz, Thomas, et al. "EMT in cancer." Nature Reviews Cancer 18.2 (2018): 128-134.
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