A diet rich in Mailllard reaction products protects LDL against copper induced oxidation ex vivo, a human intervention trial

Journal article


Publication Details

Author(s): Dittrich R, Dragonas C, Kannenkeril D, Hoffmann I, Müller A, Beckmann M, Pischetsrieder M
Journal: Food Research International
Publisher: Elsevier
Publication year: 2009
Volume: 42
Journal issue: 9
Pages range: 1315-1322
ISSN: 0963-9969


Abstract


Maillard reaction products (MRPs) have antioxidative properties in vitro but the influence of a diet rich in MRPs on oxidative damage in vivo remains unknown. In this study, the influence of thermally processed foods rich in MRPs on copper induced oxidation of human low-density lipoprotein (LDL) in vitro was examined. Moreover, oxidative resistance of LDL (OR) in blood plasma of eight healthy subjects was monitored, who consumed diets poor and rich in MRPs in

weekly turn for 3 weeks. Dark beer, bread crust, and roasted coffee led to a statisticaIly significant increased OR in vitro compared to pale beer, bread crumb, and raw coffee. The consumption of a diet rich in MRPS significantly increased plasma OR compared to the diet poor in MRPs by 35.5%. This study indicates that thermally processed foods rich in MRPs inhibit the LDL oxidation in vitro and have the ability to reduce oxidative modification of LDL in vivo.



FAU Authors / FAU Editors

Dittrich, Ralf Prof. Dr.
Professur für Experimentelle Reproduktionsmedizin
Pischetsrieder, Monika Prof. Dr.
Lehrstuhl für Lebensmittelchemie (Henriette-Schmidt-Burkhardt Lehrstuhl)


Additional Organisation
Emil-Fischer-Zentrum (Emil Fischer Center)


How to cite

APA:
Dittrich, R., Dragonas, C., Kannenkeril, D., Hoffmann, I., Müller, A., Beckmann, M., & Pischetsrieder, M. (2009). A diet rich in Mailllard reaction products protects LDL against copper induced oxidation ex vivo, a human intervention trial. Food Research International, 42(9), 1315-1322. https://dx.doi.org/10.1016/j.foodres.2009.04.007

MLA:
Dittrich, Ralf, et al. "A diet rich in Mailllard reaction products protects LDL against copper induced oxidation ex vivo, a human intervention trial." Food Research International 42.9 (2009): 1315-1322.

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Last updated on 2018-28-06 at 09:23