Solitary sarcoid granuloma of the iris mimicking tuberculosis: a case report

Beitrag in einer Fachzeitschrift

Details zur Publikation

Autorinnen und Autoren: Rejdak R, Pogorelov P, Mardin C, Szkaradek M, Jünemann A
Zeitschrift: Journal of Ophthalmology
Verlag: Hindawi Publishing Corporation
Jahr der Veröffentlichung: 2014
Band: 2014
Seitenbereich: 656042
ISSN: 2090-004X


Introduction. We report a case of a male patient presented with sarcoid lesions of the iris and conjunctiva, mimicking tuberculosis due to epithelioid cell granulomas with small central necrosis in conjunctival biopsy. Patient. A 25-year-old man was referred to our department for further management of an "iris tumor with iridocyclitis" in his right eye. Initial examination showed an isolated vascular tumor of the iris and ciliary body with anterior uveitis and mutton-fat keratic precipitates, suggesting the diagnosis of a granulomatous disease. Conjunctival biopsy revealed granulomatous epithelioid cell inflammation with small central necrosis without acid-fast bacilli. Extensive systemic examination, including bronchoscopy and transbronchial biopsy, provided the diagnosis of sarcoidosis stage 2 with pulmonary involvement, thus ruling out tuberculosis. Systemic and local steroid therapy was initiated, leading to complete recovery of our patient with complete disappearance of the iris lesion and improvement of the pulmonary function. Conclusion. Although noncaseating epithelioid cell granulomas are typical for sarcoidosis, small central necrosis can be found in some granulomas, leading to presumption of tuberculosis. Extensive systemic checkup in cooperation with other specialists is essential to confirm the correct diagnosis and to initiate the appropriate therapy.

FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Jünemann, Anselm Prof. Dr.
Medizinische Fakultät

Einrichtungen weiterer Autorinnen und Autoren

Medical University of Lublin / Uniwersytet Medyczny w Lublinie


Rejdak, R., Pogorelov, P., Mardin, C., Szkaradek, M., & Jünemann, A. (2014). Solitary sarcoid granuloma of the iris mimicking tuberculosis: a case report. Journal of Ophthalmology, 2014, 656042.

Rejdak, Robert, et al. "Solitary sarcoid granuloma of the iris mimicking tuberculosis: a case report." Journal of Ophthalmology 2014 (2014): 656042.


Zuletzt aktualisiert 2018-08-10 um 02:46