Development of curative therapies for Ewing sarcomas by interdisciplinary cooperative groups in Europe

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Boelling T, Braun-Munzinger G, Burdach S, Calaminus G, Craft A, Delattre O, Deley MCL, Dirksen U, Dockhorn-Dworniczak B, Dunst J, Engel S, Faldum A, Froehlich B, Gadner H, Goebel U, Gosheger G, Hardes J, Hawkins DS, Hjorth L, Hoffmann C, Kovar H, Kruseova J, Ladenstein R, Leuschner I, Lewis IJ, Oberlin O, Paulussen M, Potratz J, Ranft A, Roessig C, Ruebe C, Sauer R, Schober O, Schuck A, Timmermann B, Tirode F, Van Den Berg H, Van Valen F, Vieth V, Willich N, Winkelmann W, Whelan J, Womer RB
Zeitschrift: Klinische Padiatrie
Verlag: Georg Thieme Verlag
Jahr der Veröffentlichung: 2015
Band: 227
Heftnummer: 3
Seitenbereich: 108-15
ISSN: 0300-8630


Abstract

Curative therapies for Ewing sarcoma have been developed within cooperative groups. Consecutive clinical trials have systematically assessed the impact and timing of local therapy and the activity of cytotoxic drugs and their combinations. They have led to an increase of long-term disease-free survival to around 70% in patients with localized disease. Translational research in ES remains an area in which interdisciplinary and international cooperation is essential for future progress. This article reviews current state-of-the art therapy, with a focus on trials performed in Europe, and summarizes novel strategies to further advance both the cure rates and quality of survival.


Autor(en) der externen Einrichtung(en)
Alder Hey Children's Hospital
Christian-Albrechts-Universität zu Kiel
Heinrich-Heine-Universität Düsseldorf
Institut Gustave-Roussy
King's College Hospital (KCH)
Klinikum Kempten
Lund University / Lunds universitet
National Institute for Health and Medical Research / Institut national de la santé et de la recherche médicale (INSERM)
Private Universität Witten/Herdecke gGmbH
Royal Victoria Infirmary
St. Anna Kinderkrebsforschung
Technische Universität München (TUM)
Universität des Saarlandes (UdS)
Universitätsklinikum Essen
Universitätsklinikum Münster
Universität zu Lübeck
University of Amsterdam
University of Paris 11 - Paris-Sud / Université Paris XI Paris-Sud
University of Pennsylvania
University of Washington
Univerzita Karlova v Praze / Charles University in Prague
Westfälische Wilhelms-Universität (WWU) Münster
Zentrum für Strahlentherapie Rheine-Osnabrück


Zitierweisen

APA:
Boelling, T., Braun-Munzinger, G., Burdach, S., Calaminus, G., Craft, A., Delattre, O.,... Womer, R.B. (2015). Development of curative therapies for Ewing sarcomas by interdisciplinary cooperative groups in Europe. Klinische Padiatrie, 227(3), 108-15. https://dx.doi.org/10.1055/s-0035-1545263

MLA:
Boelling, T., et al. "Development of curative therapies for Ewing sarcomas by interdisciplinary cooperative groups in Europe." Klinische Padiatrie 227.3 (2015): 108-15.

BibTeX: 

Zuletzt aktualisiert 2018-08-10 um 02:30