Ultrasonic elasticity determination of 45S5 Bioglass®-based scaffolds: Influence of polymer coating and crosslinking treatment

Journal article
(Original article)


Publication Details

Author(s): Li W, Pastrama MI, Ding Y, Zheng K, Hellmich C, Boccaccini AR
Journal: Journal of the Mechanical Behavior of Biomedical Materials
Publisher: Elsevier
Publication year: 2014
Volume: 40
Pages range: 85-94
ISSN: 1878-0180


Abstract


Highly porous 45S5 Bioglass-based scaffolds with interconnected pore structure are promising candidates for bone tissue engineering due to their bioactivity, biocompatibility, osteogenic and angiogenic effects. In the present study, to ensure the mechanical competence of the 45S5 Bioglass-based scaffolds, their stiffness was adjusted by applying polymer coatings and further crosslinking treatment. A non-destructive ultrasonic technique was used to determine the stiffness of the scaffolds. The stiffness of uncoated scaffolds was shown to increase by applying polymer coatings, and a further increase was achieved by crosslinking the used polymer coatings. All uncoated and polymer-coated scaffolds were confirmed to exhibit stiffness values in the range of reported values in the literature for cancellous bone. A statistical evaluation of combined multiscale ultrasound-nanoindentation measurements indicated that the stiffness of the coated scaffold is directly dependent on the stiffness of the polymer coating.



FAU Authors / FAU Editors

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Ding, Yaping
Lehrstuhl für Werkstoffwissenschaften (Polymerwerkstoffe)
Li, Wei
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Zheng, Kai Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)


External institutions with authors

Technische Universität Wien


How to cite

APA:
Li, W., Pastrama, M.-I., Ding, Y., Zheng, K., Hellmich, C., & Boccaccini, A.R. (2014). Ultrasonic elasticity determination of 45S5 Bioglass®-based scaffolds: Influence of polymer coating and crosslinking treatment. Journal of the Mechanical Behavior of Biomedical Materials, 40, 85-94. https://dx.doi.org/10.1016/j.jmbbm.2014.08.010

MLA:
Li, Wei, et al. "Ultrasonic elasticity determination of 45S5 Bioglass®-based scaffolds: Influence of polymer coating and crosslinking treatment." Journal of the Mechanical Behavior of Biomedical Materials 40 (2014): 85-94.

BibTeX: 

Last updated on 2019-17-05 at 07:32