Biological impact of bioactive glasses and their dissolution products

Article in Edited Volumes


Publication Details

Author(s): Hoppe A, Boccaccini AR
Editor(s): Deb S. (London)
Title edited volumes: Biomaterials for Oral and Craniomaxillofacial Applications
Publisher: Karger AG
Publication year: 2015
Volume: 17
Pages range: 22-32
ISBN: 9783318024609
ISSN: 1420-2433
eISSN: 1662-3770


Abstract


For many years, bioactive glasses (BGs) have been widely considered for bone tissue engineering applications due to their ability to bond to hard as well as soft tissue (a property termed bioactivity) and for their stimulating ef'fects on bone formation. Ionic dissolution products re'leased during the degradation of the BG matrix induce osteogenic gene expression leading to enhanced bone regeneration. Recently, adding bioactive metallic ions (e.g. boron, copper, cobalt, silver, zinc and strontium) to silicate (or phosphate and borate) glasses has emerged as a promising route for developing novel BG formulations with specific therapeutic functionalities, including anti'bacterial, angiogenic and osteogenic properties. The deg'radation behaviour of BGs can be tailored by adjusting the glass chemistry making these glass matrices potential car'rier systems for controlled therapeutic ion release. This book chapter summarises the fundamental aspects of the effect of ionic dissolution products from BGs on osteo'genesis and angiogenesis, whilst discussing novel BG compositions with controlled therapeutic ion release.



FAU Authors / FAU Editors

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Hoppe, Alexander
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)


How to cite

APA:
Hoppe, A., & Boccaccini, A.R. (2015). Biological impact of bioactive glasses and their dissolution products. In Deb S. (London) (Eds.), Biomaterials for Oral and Craniomaxillofacial Applications. (pp. 22-32). Karger AG.

MLA:
Hoppe, Alexander, and Aldo R. Boccaccini. "Biological impact of bioactive glasses and their dissolution products." Biomaterials for Oral and Craniomaxillofacial Applications. Ed. Deb S. (London), Karger AG, 2015. 22-32.

BibTeX: 

Last updated on 2019-22-08 at 21:50