Slow-theta power decreases during item-place encoding predict spatial accuracy of subsequent context recall
Crespo-Garcia M, Zeiller M, Leupold C, Kreiselmeyer G, Rampp S, Hamer H, Dalal SS (2016)
Publication Type: Journal article
Publication year: 2016
Journal
Book Volume: 142
Pages Range: 533-543
DOI: 10.1016/j.neuroimage.2016.08.021
Abstract
Human hippocampal theta oscillations play a key role in accurate spatial coding. Associative encoding involves similar hippocampal networks but, paradoxically, is also characterized by theta power decreases. Here, we investigated how theta activity relates to associative encoding of place contexts resulting in accurate navigation. Using MEG, we found that slow-theta (2-5Hz) power negatively correlated with subsequent spatial accuracy for virtual contextual locations in posterior hippocampus and other cortical structures involved in spatial cognition. A rare opportunity to simultaneously record MEG and intracranial EEG in an epilepsy patient provided crucial insights: during power decreases, slow-theta in right anterior hippocampus and left inferior frontal gyrus phase-led the left temporal cortex and predicted spatial accuracy. Our findings indicate that decreased slow-theta activity reflects local and long-range neural mechanisms that encode accurate spatial contexts, and strengthens the view that local suppression of low-frequency activity is essential for more efficient processing of detailed information.
Authors with CRIS profile
Gernot Kreiselmeyer
Department of Neurology
Stefan Rampp
Department of Neurosurgery
Hajo Hamer
Professur für Epileptologie
Involved external institutions
Germany (DE)How to cite
APA:
Crespo-Garcia, M., Zeiller, M., Leupold, C., Kreiselmeyer, G., Rampp, S., Hamer, H., & Dalal, S.S. (2016). Slow-theta power decreases during item-place encoding predict spatial accuracy of subsequent context recall. NeuroImage, 142, 533-543. https://dx.doi.org/10.1016/j.neuroimage.2016.08.021
MLA:
Crespo-Garcia, Maite, et al. "Slow-theta power decreases during item-place encoding predict spatial accuracy of subsequent context recall." NeuroImage 142 (2016): 533-543.
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