Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

Tsai TH, Potsaid B, Tao YK, Jayaraman V, Jiang J, Heim PJS, Kraus M, Zhou C, Hornegger J, Mashimo H, Cable AE, Fujimoto JG (2013)

Publication Type: Journal article

Publication year: 2013

Journal

Biomedical Optics Express Optical Society of America

Publisher: Optical Society of America

Book Volume: 4

Pages Range: 1119-1132

Journal Issue: 7

DOI: 10.1364/BOE.4.001119

Abstract

We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed endoscopic swept source optical coherence tomography (OCT) using a vertical cavity surfaceemitting laser (VCSEL) at a 1 MHz axial scan rate. The micromotor can rotate a micro-prism at several hundred frames per second with less than 5 V drive voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back to acquire a three-dimensional (3D) data set covering a large area on the specimen. The VCSEL provides a high axial scan rate to support dense sampling under high frame rate operation. Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 μm axial resolution, 8 μm lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated. © 2013 Optical Society of America.

Authors with CRIS profile

Martin Kraus Lehrstuhl für Informatik 14 (Bild- und Sprachverarbeitung) Joachim Hornegger Lehrstuhl für Informatik 14 (Bild- und Sprachverarbeitung)

Involved external institutions

Massachusetts Institute of Technology (MIT) US United States (USA) (US) Praevium Research, Inc. US United States (USA) (US) Advanced Imaging Group, Thorlabs Inc. US United States (USA) (US) Thorlabs Quantum Electronics, Inc. US United States (USA) (US) Veterans Affairs Healthcare System Boston and Harvard Medical School US United States (USA) (US)

How to cite

APA:

Tsai, T.-H., Potsaid, B., Tao, Y.K., Jayaraman, V., Jiang, J., Heim, P.J.S.,... Fujimoto, J.G. (2013). Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology. Biomedical Optics Express, 4(7), 1119-1132. https://dx.doi.org/10.1364/BOE.4.001119

MLA:

Tsai, Tsung-Han, et al. "Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology." Biomedical Optics Express 4.7 (2013): 1119-1132.

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