The use of clinical experience to stage the severity of functional impairments in Alzheimer's disease

Finkel S, Bergener M, Hulla F, Stemmler M, Overall J (1996)

Publication Type: Journal article

Publication year: 1996

Journal

Human Psychopharmacology-Clinical and Experimental Wiley-Blackwell

Publisher: Wiley-Blackwell

Book Volume: 11

Pages Range: 439-449

Journal Issue: 6

DOI: 10.1002/(SICI)1099-1077(199611)11:63.3.CO;2-B

Abstract

Examined international consistency and elucidated internationally-based clinical understanding of the chronology of increasing functional impairment in Alzheimer's disease (AD). 28 experienced clinicians from Germany and the US rated the stage of AD at which each of the 44 manifestations of cognitive, behavioral, or functional impairment is most clinically relevant. Data were subjected to 3 methods of metric scale analysis: equal appearing intervals, principal components, and paired comparison scaling. Finally, a single average T-score value for each item was calculated, and the 44 items were listed in rank order according to their average severity scale values. The resulting ordering and associated scale values provided a consistent and reliable description of the course of functional impairments in AD as seen by experienced clinicians in the 2 countries.

Authors with CRIS profile

Mark Stemmler Lehrstuhl für Psychologische Diagnostik, Methodenlehre und Rechtspsychologie

Involved external institutions

Northwestern University US United States (USA) (US) Johannes-Klinik Altenberge DE Germany (DE) Bayer HealthCare AG DE Germany (DE) University of Texas at Austin US United States (USA) (US)

How to cite

APA:

Finkel, S., Bergener, M., Hulla, F., Stemmler, M., & Overall, J. (1996). The use of clinical experience to stage the severity of functional impairments in Alzheimer's disease. Human Psychopharmacology-Clinical and Experimental, 11(6), 439-449. https://dx.doi.org/10.1002/(SICI)1099-1077(199611)11:63.3.CO;2-B

MLA:

Finkel, Sanford, et al. "The use of clinical experience to stage the severity of functional impairments in Alzheimer's disease." Human Psychopharmacology-Clinical and Experimental 11.6 (1996): 439-449.

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