Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation

Garn H, Bahn S, Baune BT, Binder EB, Bisgaard H, Chatila TA, Chavakis T, Culmsee C, Dannlowski U, Gay S, Gern J, Haahtela T, Kircher T, Mueller-Ladner U, Neurath M, Preissner KT, Reinhardt C, Rook G, Russell S, Schmeck B, Stappenbeck T, Steinhoff U, Van Os J, Weiss S, Zemlin M, Renz H (2016)

Publication Type: Journal article

Publication year: 2016

Journal

Book Volume: 138

Pages Range: 47-56

Journal Issue: 1

DOI: 10.1016/j.jaci.2016.02.046

Abstract

Recent research indicates that chronic inflammatory diseases, including allergies and autoimmune and neuropsychiatric diseases, share common pathways of cellular and molecular dysregulation. It was the aim of the International von-Behring-Röntgen Symposium (October 16-18, 2014, in Marburg, Germany) to discuss recent developments in this field. These include a concept of biodiversity; the contribution of urbanization, lifestyle factors, and nutrition (eg, vitamin D); and new mechanisms of metabolic and immune dysregulation, such as extracellular and intracellular RNAs and cellular and mitochondrial stress. Epigenetic mechanisms contribute further to altered gene expression and therefore to the development of chronic inflammation. These novel findings provide the foundation for further development of preventive and therapeutic strategies.

Authors with CRIS profile

Involved external institutions

Philipps-Universität Marburg Germany (DE) University of Cambridge United Kingdom (GB) University of Adelaide Australia (AU) Max-Planck-Institut für Psychiatrie (Deutsche Forschungsanstalt für Psychiatrie) Germany (DE) University of Copenhagen Denmark (DK) Harvard University United States (USA) (US) Technische Universität Dresden Germany (DE) Westfälische Wilhelms-Universität (WWU) Münster Germany (DE) Universitätsspital Zürich (USZ) Switzerland (CH) Helsinki University Central Hospital (HUCH) / Helsingin seudun yliopistollinen keskussairaala (HYKS) Finland (FI) Justus-Liebig-Universität Gießen Germany (DE) Universitätsmedizin der Johannes Gutenberg-Universität Mainz Germany (DE) University College London (UCL) United Kingdom (GB) University of British Columbia Canada (CA) Washington University United States (USA) (US) Maastricht University Netherlands (NL)

How to cite

APA:

Garn, H., Bahn, S., Baune, B.T., Binder, E.B., Bisgaard, H., Chatila, T.A.,... Renz, H. (2016). Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. Journal of Allergy and Clinical Immunology, 138(1), 47-56. https://dx.doi.org/10.1016/j.jaci.2016.02.046

MLA:

Garn, Holger, et al. "Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation." Journal of Allergy and Clinical Immunology 138.1 (2016): 47-56.

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