Cellular interfaces with hydrogen-bonded organic semiconductor hierarchical nanocrystals

Journal article


Publication Details

Author(s): Sytnyk M, Jakesova M, Litvinukova M, Mashkov O, Kriegner D, Stangl J, Nebesarova J, Fecher FW, Schoefberger W, Sariciftci NS, Schindl R, Heiß W, Glowacki ED
Journal: Nature Communications
Publisher: NATURE PUBLISHING GROUP
Publication year: 2017
Volume: 8
ISSN: 2041-1723
Language: English


Abstract


Successful formation of electronic interfaces between living cells and semiconductors hinges on being able to obtain an extremely close and high surface-area contact, which preserves both cell viability and semiconductor performance. To accomplish this, we introduce organic semiconductor assemblies consisting of a hierarchical arrangement of nanocrystals. These are synthesised via a colloidal chemical route that transforms the nontoxic commercial pigment quinacridone into various biomimetic three-dimensional arrangements of nanocrystals. Through a tuning of parameters such as precursor concentration, ligands and additives, we obtain complex size and shape control at room temperature. We elaborate hedgehog-shaped crystals comprising nanoscale needles or daggers that form intimate interfaces with the cell membrane, minimising the cleft with single cells without apparent detriment to viability. Excitation of such interfaces with light leads to effective cellular photostimulation. We find reversible light-induced conductance changes in ion-selective or temperature-gated channels.



FAU Authors / FAU Editors

Heiß, Wolfgang Prof. Dr.
Professur für Werkstoffwissenschaften (lösungsprozessierte Halbleitermaterialien)
Mashkov, Oleksandr
Institute Materials for Electronics and Energy Technology (i-MEET)
Sytnyk, Mykhailo
Institute Materials for Electronics and Energy Technology (i-MEET)


Additional Organisation
Technische Fakultät
Institute Materials for Electronics and Energy Technology (i-MEET)


External institutions with authors

Academy of Sciences of the Czech Republic (ASCR) / Akademie věd České republiky (AVČR)
Bayerisches Zentrum für Angewandte Energieforschung e.V. (ZAE Bayern)
Johannes Kepler Universität (JKU) Linz
Univerzita Karlova v Praze / Charles University in Prague


Research Fields

Neue Materialien und Prozesse
Research focus area of a faculty: Technische Fakultät


How to cite

APA:
Sytnyk, M., Jakesova, M., Litvinukova, M., Mashkov, O., Kriegner, D., Stangl, J.,... Glowacki, E.D. (2017). Cellular interfaces with hydrogen-bonded organic semiconductor hierarchical nanocrystals. Nature Communications, 8. https://dx.doi.org/10.1038/s41467-017-00135-0

MLA:
Sytnyk, Mykhailo, et al. "Cellular interfaces with hydrogen-bonded organic semiconductor hierarchical nanocrystals." Nature Communications 8 (2017).

BibTeX: 

Last updated on 2018-25-10 at 12:04