HIF meets NF-?B signaling

Willam C (2014)

Publication Type: Journal article, Note

Publication year: 2014

Journal

Kidney International Nature Publishing Group: Open Access Hybrid Model Option A

Book Volume: 85

Pages Range: 232-4

Journal Issue: 2

DOI: 10.1038/ki.2013.362

Abstract

An inflammatory stimulus prior to an ischemic insult can be protective in acute kidney injury (AKI) as well as other acute organ injury models, an effect called cross-tolerance. He et al. investigated mechanisms of cross-tolerance whereby pretreatment with lipopolysaccharide (LPS) protects from a subsequent ischemic insult of the kidney. The protection was mediated by LPS-induced nuclear factor-?B and hypoxia-inducible factor-2? (HIF-2?) signaling. These results link two central cellular pathways and give new insight into HIF-mediated renoprotection in AKI models.

Authors with CRIS profile

Carsten Willam Department of Medicine 4 – Nephrology and Hypertension

How to cite

APA:

Willam, C. (2014). HIF meets NF-?B signaling. Kidney International, 85(2), 232-4. https://doi.org/10.1038/ki.2013.362

MLA:

Willam, Carsten. "HIF meets NF-?B signaling." Kidney International 85.2 (2014): 232-4.

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