Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis

Atreya R, Buelte M, Gerlach GF, Goethe R, Hornef MW, Koehler H, Meens J, Moebius P, Roeb E, Weiss S (2014)

Publication Type: Journal article

Publication year: 2014

Journal

International Journal of Medical Microbiology Elsevier

Book Volume: 304

Pages Range: 858-67

Journal Issue: 7

DOI: 10.1016/j.ijmm.2014.07.006

Abstract

Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of paratuberculosis (Johne's disease [JD]), a chronic granulomatous enteritis in ruminants. JD is one of the most widespread bacterial diseases of domestic animals with significant economic impact. The histopathological picture of JD resembles that of Crohn's disease (CD), a human chronic inflammatory bowel disease of still unresolved aetiology. An aetiological relevance of MAP for CD has been proposed. This and the ambiguity of other published epidemiological findings raise the question whether MAP represents a zoonotic agent. In this review, we will discuss evidence that MAP has zoonotic capacity.

Authors with CRIS profile

Raja Atreya Professur für Translationale Immunforschung bei chronisch entzündlichen Darmerkrankungen (Heisenberg-Professur)

Involved external institutions

Helmholtz-Zentrum für Infektionsforschung (HZI) DE Germany (DE) Justus-Liebig-Universität Gießen DE Germany (DE) Friedrich-Loeffler-Institut (FLI), Bundesforschungsinstitut für Tiergesundheit DE Germany (DE) Stiftung Tierärztliche Hochschule Hannover (TiHo) DE Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School DE Germany (DE) IVD Gesellschaft für innovative Veterinärdiagnostik mbH DE Germany (DE)

How to cite

APA:

Atreya, R., Buelte, M., Gerlach, G.-F., Goethe, R., Hornef, M.W., Koehler, H.,... Weiss, S. (2014). Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis. International Journal of Medical Microbiology, 304(7), 858-67. https://dx.doi.org/10.1016/j.ijmm.2014.07.006

MLA:

Atreya, Raja, et al. "Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis." International Journal of Medical Microbiology 304.7 (2014): 858-67.

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