The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases

Journal article


Publication Details

Author(s): Reijs BLR, Teunissen CE, Goncharenko N, Betsou F, Blennow K, Baldeiras I, Brosseron F, Cavedo E, Fladby T, Froelich L, Gabryelewicz T, Gurvit H, Kapaki E, Koson P, Kulic L, Lehmann S, Lewczuk P, Lleo A, Maetzler W, De Mendonca A, Miller AM, Molinuevo JL, Mollenhauer B, Parnetti L, Rot U, Schneider A, Simonsen AH, Tagliavini F, Tsolaki M, Verbeek MM, Verhey FRJ, Zboch M, Winblad B, Scheltens P, Zetterberg H, Visser PJ
Journal: Frontiers in Neurology
Publication year: 2015
Volume: 6
Pages range: 216
ISSN: 1664-2295


Abstract

Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme-Neurodegenerative Disease Research, which aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer's disease (AD) and Parkinson's disease (PD). The objective was to standardize the assessment of existing assays and to validate novel fluid biomarkers for AD and PD. To support the validation of novel biomarkers and assays, a central and a virtual biobank for body fluids and associated data from subjects with neurodegenerative diseases have been established. In the central biobank, cerebrospinal fluid (CSF) and blood samples were collected according to the BIOMARKAPD standardized pre-analytical procedures and stored at Integrated BioBank of Luxembourg. The virtual biobank provides an overview of available CSF, plasma, serum, and DNA samples at each site. Currently, at the central biobank of BIOMARKAPD samples are available from over 400 subjects with normal cognition, mild cognitive impairment (MCI), AD, frontotemporal dementia (FTD), vascular dementia, multiple system atrophy, progressive supranuclear palsy, PD, PD with dementia, and dementia with Lewy bodies. The virtual biobank contains information on over 8,600 subjects with varying diagnoses from 21 local biobanks. A website has been launched to enable sample requests from the central biobank and virtual biobank.


FAU Authors / FAU Editors

Lewczuk, Piotr Prof. Dr.
Psychiatrische und Psychotherapeutische Klinik


External institutions with authors

Akershus University Hospital / Akershus universitetssykehus (Ahus)
Aristotle University of Thessaloniki
Copenhagen University Hospital
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)
Eberhard Karls Universität Tübingen
Foundation of the Carlo Besta Neurological Institute (IRCCS)
Hospital Clínic de Barcelona
Hospital de la Santa Creu i Sant Pau
Integrated Biobank of Luxembourg: IBBL
IRCCS Fatebenefratelli - Brescia
Istanbul University / İstanbul Üniversitesi
Karolinska Institute
Ljubljana University Medical Centre (Ljubljana UMC) / Univerzitetni klinični center Ljubljana
Maastricht University
National and Kapodistrian University of Athens
Paracelsus-Elena-Klinik Kassel
Polska Akademia Nauk (PAN) / Polish Academy of Sciences
Radboud University Nijmegen
Ruprecht-Karls-Universität Heidelberg
Slovak Medical University (SMU) / Slovenská zdravotnícka univerzita v Bratislave
Trinity College Dublin
Universidade de Coimbra
Università degli Studi di Perugia
Universitätsklinikum Göttingen
Universität Zürich (UZH)
University of Gothenburg / Göteborgs universitet
University of Lisbon / Universidade de Lisboa (ULisboa)
University of Montpellier / Université Montpellier
Vrije Universiteit Amsterdam (VU) / University Amsterdam
Wrocław Medical University / Uniwersytet Medyczny we Wrocławiu


How to cite

APA:
Reijs, B.L.R., Teunissen, C.E., Goncharenko, N., Betsou, F., Blennow, K., Baldeiras, I.,... Visser, P.J. (2015). The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases. Frontiers in Neurology, 6, 216. https://dx.doi.org/10.3389/fneur.2015.00216

MLA:
Reijs, Babette L. R., et al. "The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases." Frontiers in Neurology 6 (2015): 216.

BibTeX: 

Last updated on 2019-01-07 at 09:20