Knee joint subchondral bone structure alterations in active athletes: a cross-sectional case-control study

Roemer F, Jarraya M, Niu J, Duryea J, Lynch JA, Guermazi A (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Osteoarthritis and Cartilage Elsevier

Book Volume: 23

Pages Range: 2184-90

Journal Issue: 12

DOI: 10.1016/j.joca.2015.07.002

Abstract

It has been shown that trabecular bone structure parameters extracted from radiographs known as fractal signature analysis (FSA) are able to predict structural outcomes such as radiographic osteoarthritis (OA) progression. Little is known about their involvement in early disease or about differences between subjects exposed to increased joint loading such as young active athletes compared to non-athletes. Aim was to compare horizontal and vertical dimensions of bone texture considering athlete status, gender, previous anterior cruciate ligament (ACL) surgery and age.Included were 685 patients of which 135 consecutive athletes (82% soccer players) 18-36 years old and 550 non-athletes controls in the same age range had knee radiography for assessment of subacute or chronic knee complaints. Regions of interest (ROI) were placed in the subchondral medial and lateral tibial plateaus. Fractal signatures were calculated in the horizontal and vertical dimensions. Curve fitting algorithms were applied taking into account all four risk factors in the same model adjusting for each other.For the horizontal dimensions significant differences were observed for gender (estimate (E) 0.098 (95% confidence interval(CI)) (-0.009, 0.008), P < .0001), previous ACL surgery (E -0.031, 95% CI (-0.043, -0.019), P < .0001) and highest age group (E -0.039, 95% CI (-0.048, -0.029), P < .0001). For vertical dimensions, significant differences were shown for athletes (E -0.012, 95% CI (-0.020, -0.004), P < .0001), gender (E 0.056, 95% CI (0.049, 0.062), P < .0001), and age range from 28 to 32 years (E -0.028, 95% CI (-0.037, -0.019), P < .0001).Trabecular bone structure differs between athletes and non-athletes, in regard to previous ACL surgery, gender and higher age.

Authors with CRIS profile

Frank Roemer Institute of Radiology

Involved external institutions

Aspetar - Orthopaedic and Sports Medicine Hospital /سبيتار QA Qatar (QA) University of California San Francisco (UCSF) US United States (USA) (US) Harvard University US United States (USA) (US) Boston University US United States (USA) (US)

How to cite

APA:

Roemer, F., Jarraya, M., Niu, J., Duryea, J., Lynch, J.A., & Guermazi, A. (2015). Knee joint subchondral bone structure alterations in active athletes: a cross-sectional case-control study. Osteoarthritis and Cartilage, 23(12), 2184-90. https://doi.org/10.1016/j.joca.2015.07.002

MLA:

Roemer, Frank, et al. "Knee joint subchondral bone structure alterations in active athletes: a cross-sectional case-control study." Osteoarthritis and Cartilage 23.12 (2015): 2184-90.

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