Unsupervised Unstained Cell Detection by SIFT Keypoint Clustering and Self-labeling Algorithm

Conference contribution
(Original article)


Publication Details

Author(s): Mualla F, Schöll S, Sommerfeldt B, Maier A, Steidl S, Buchholz R, Hornegger J
Title edited volumes: Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Publication year: 2014
Conference Proceedings Title: Lecture Notes in Computer Science, Volume 8675, MICCAI 2014 Proceedings, Part III
Pages range: 377-384


Abstract


We propose a novel unstained cell detection algorithm based on unsupervised learning. The algorithm utilizes the scale invariant feature transform (SIFT), a self-labeling algorithm, and two clustering steps in order to achieve high performance in terms of time and detection accuracy. Unstained cell imaging is dominated by phase contrast and bright field microscopy. Therefore, the algorithm was assessed on images acquired using these two modalities. Five cell lines having in total 37 images and 7250 cells were considered for the evaluation: CHO, L929, Sf21, HeLa, and Bovine cells. The obtained F-measures were between 85.1 and 89.5. Compared to the state-of-the-art, the algorithm achieves very close F-measure to the supervised approaches in much less time.



FAU Authors / FAU Editors

Buchholz, Rainer Prof. Dr.
Lehrstuhl für Bioverfahrenstechnik
Hornegger, Joachim Prof. Dr.-Ing.
Lehrstuhl für Informatik 5 (Mustererkennung)
Maier, Andreas Prof. Dr.-Ing.
Lehrstuhl für Informatik 5 (Mustererkennung)
Mualla, Firas
Lehrstuhl für Informatik 5 (Mustererkennung)
Schöll, Simon
Lehrstuhl für Informatik 5 (Mustererkennung)
Sommerfeldt, Björn
Lehrstuhl für Bioverfahrenstechnik
Steidl, Stefan PD Dr.-Ing.
Lehrstuhl für Informatik 5 (Mustererkennung)


How to cite

APA:
Mualla, F., Schöll, S., Sommerfeldt, B., Maier, A., Steidl, S., Buchholz, R., & Hornegger, J. (2014). Unsupervised Unstained Cell Detection by SIFT Keypoint Clustering and Self-labeling Algorithm. In Lecture Notes in Computer Science, Volume 8675, MICCAI 2014 Proceedings, Part III (pp. 377-384). Boston, MA, USA.

MLA:
Mualla, Firas, et al. "Unsupervised Unstained Cell Detection by SIFT Keypoint Clustering and Self-labeling Algorithm." Proceedings of the Medical Image Computing and Computer-Assisted Intervention – MICCAI 2014, Boston, MA, USA 2014. 377-384.

BibTeX: 

Last updated on 2018-19-04 at 02:53