45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering

Journal article
(Original article)


Publication Details

Author(s): Li W, Garmendia N, De Larraya UP, Ding Y, Detsch R, Gruenewald A, Roether J, Schubert DW, Boccaccini AR
Journal: RSC Advances
Publisher: Royal Society of Chemistry
Publication year: 2014
Volume: 4
Journal issue: 99
Pages range: 56156-56164
ISSN: 2046-2069


Abstract


Highly porous 45S5 bioactive glass-based scaffolds prepared by foam replication method were coated with cellulose nanowhiskers by dip coating method. The obtained cellulose nanowhisker-coated scaffolds retained the high porosity and interconnected pore structure. The cellulose coating improved the mechanical properties of the scaffolds and did not hinder their bioactivity in simulated body fluid. In vitro biocompatibility assessment was carried out by qualitative evaluation of the morphology of osteoblast-like cells (MG-63) seeded onto the scaffolds. The cells were shown to attach and spread on both uncoated scaffolds and cellulose nanowhisker-coated scaffolds, thus cellulose nanowhisker coating seems to have no negative influence on the behavior of MG-63 cells. The obtained bioactive and biocompatible composite scaffolds represent promising candidates for bone tissue engineering applications.



FAU Authors / FAU Editors

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Detsch, Rainer Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Ding, Yaping
Lehrstuhl für Werkstoffwissenschaften (Polymerwerkstoffe)
Li, Wei
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Roether, Judith
Lehrstuhl für Werkstoffwissenschaften (Polymerwerkstoffe)
Schubert, Dirk W. Prof. Dr.
Lehrstuhl für Werkstoffwissenschaften (Polymerwerkstoffe)


External institutions with authors

Centro Multidisciplinar de Tecnologias para la Industria (CEMITEC)


How to cite

APA:
Li, W., Garmendia, N., De Larraya, U.P., Ding, Y., Detsch, R., Gruenewald, A.,... Boccaccini, A.R. (2014). 45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering. RSC Advances, 4(99), 56156-56164. https://dx.doi.org/10.1039/c4ra07740g

MLA:
Li, Wei, et al. "45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering." RSC Advances 4.99 (2014): 56156-56164.

BibTeX: 

Last updated on 2019-06-04 at 21:51

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