The molecular mechanics of mixed lineage leukemia

Slany R (2016)


Publication Status: Published

Publication Type: Journal article, Review article

Publication year: 2016

Journal

Publisher: Nature Publishing Group

Book Volume: 35

Pages Range: 5215-5223

Journal Issue: 40

DOI: 10.1038/onc.2016.30

Abstract

Mixed lineage leukemia caused by MLL fusion proteins is still a mostly incurable disease. Research on novel treatment strategies has gained momentum in the last years with the elucidation of the molecular mechanisms underlying the transforming potential of these powerful oncoproteins. This review summarizes the recent developments in this area including new attempts to treat MLL in a rational way by exploiting the biochemical vulnerabilities of the leukemogenic process.

Authors with CRIS profile

How to cite

APA:

Slany, R. (2016). The molecular mechanics of mixed lineage leukemia. Oncogene, 35(40), 5215-5223. https://doi.org/10.1038/onc.2016.30

MLA:

Slany, Robert. "The molecular mechanics of mixed lineage leukemia." Oncogene 35.40 (2016): 5215-5223.

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