Fcgamma receptors as regulators of immune responses.

Nimmerjahn F, Ravetch JV (2008)


Publication Status: Published

Publication Type: Journal article, Review article

Publication year: 2008

Journal

Book Volume: 8

Pages Range: 34-47

Journal Issue: 1

DOI: 10.1038/nri2206

Abstract

In addition to their role in binding antigen, antibodies can regulate immune responses through interacting with Fc receptors (FcRs). In recent years, significant progress has been made in understanding the mechanisms that regulate the activity of IgG antibodies in vivo. In this Review, we discuss recent studies addressing the multifaceted roles of FcRs for IgG (FcgammaRs) in the immune system and how this knowledge could be translated into novel therapeutic strategies to treat human autoimmune, infectious or malignant diseases.

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How to cite

APA:

Nimmerjahn, F., & Ravetch, J.V. (2008). Fcgamma receptors as regulators of immune responses. Nature reviews. Immunology, 8(1), 34-47. https://doi.org/10.1038/nri2206

MLA:

Nimmerjahn, Falk, and J. V. Ravetch. "Fcgamma receptors as regulators of immune responses." Nature reviews. Immunology 8.1 (2008): 34-47.

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