Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions

Journal article
(Original article)


Publication Details

Author(s): Schmiele M, Busch S, Morhenn H, Schindler T, Schmutzler T, Schweins R, Lindner P, Boesecke P, Westermann M, Steiniger F, Funari SS, Unruh T, Schindler T
Journal: The Journal of Physical Chemistry B
Publisher: American Chemical Society
Publication year: 2016
Volume: 120
Journal issue: 24
Pages range: 5505-5512
ISSN: 1520-5207


Abstract


The structure of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)-stabilized colloidal tetracosane emulsions was investigated by photon correlation spectroscopy and small-angle X-ray and neutron scattering, using emulsions with different neutron scattering contrasts. Special emphasis was placed on the structure of the DMPC stabilizer layer covering the emulsion droplets. A monolayer, structurally similar to a half DMPC bilayer, with a thickness of 16 Å is found. Thereby, the phosphocholine headgroups arrange flat at the oil-water interface. A deep penetration of the tetracosane oil into the stabilizer layer can be ruled out.



FAU Authors / FAU Editors

Schindler, Torben
Professur für Nanomaterialcharakterisierung (Streumethoden)
Schindler, Torben
Lehrstuhl für Kristallographie und Strukturphysik
Schmiele, Martin
Professur für Nanomaterialcharakterisierung (Streumethoden)
Schmutzler, Tilo
Professur für Nanomaterialcharakterisierung (Streumethoden)
Unruh, Tobias Prof. Dr.
Professur für Nanomaterialcharakterisierung (Streumethoden)


Additional Organisation
Graduiertenkolleg 1896/2 In situ Mikroskopie mit Elektronen, Röntgenstrahlen und Rastersonden
Exzellenz-Cluster Engineering of Advanced Materials


How to cite

APA:
Schmiele, M., Busch, S., Morhenn, H., Schindler, T., Schmutzler, T., Schweins, R.,... Schindler, T. (2016). Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions. The Journal of Physical Chemistry B, 120(24), 5505-5512. https://dx.doi.org/10.1021/acs.jpcb.6b02519

MLA:
Schmiele, Martin, et al. "Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions." The Journal of Physical Chemistry B 120.24 (2016): 5505-5512.

BibTeX: 

Last updated on 2018-19-04 at 03:52