Demyelinating disease and anti-N-methyl-D-aspartate receptor immunoglobulin G antibodies: a case report
Waschbisch A, Kallmünzer B, Schwab S, Gölitz P, Vincent A, Lee DH, Linker R (2014)
Publication Type: Journal article
Publication year: 2014
Journal
Book Volume: 7
Pages Range: 948
Abstract
Anti-N-methyl-D-aspartate receptor immunoglobulin G antibodies directed against the GluN1 subunit are considered highly specific for anti-N-methyl-D-aspartate receptor encephalitis, a severe clinical syndrome characterized by seizures, psychiatric symptoms, orofacial dyskinesia and autonomic dysfunction.Here we report a 33 year old Caucasian male patient with clinically definite multiple sclerosis who was found to be positive for anti-N-methyl-D-aspartate receptor antibodies. Rituximab therapy was initiated. On the 18 months follow-up visit the patient was found to be clinically stable, without typical signs of anti-N-methyl-D-aspartate receptor encephalitis.Our findings add to the growing evidence for a possible association between anti-N-methyl-D-aspartate receptor encephalitis and demyelinating diseases.
Authors with CRIS profile
Anne Waschbisch
Department of Neurology
Bernd Kallmünzer
Medizinische Fakultät
Stefan Schwab
Lehrstuhl für Neurologie
Philipp Gölitz
Medizinische Fakultät
Ralf Linker
Department of Neurology
Involved external institutions
United Kingdom (GB)How to cite
APA:
Waschbisch, A., Kallmünzer, B., Schwab, S., Gölitz, P., Vincent, A., Lee, D.H., & Linker, R. (2014). Demyelinating disease and anti-N-methyl-D-aspartate receptor immunoglobulin G antibodies: a case report. BMC Research Notes, 7, 948. https://dx.doi.org/10.1186/1756-0500-7-948
MLA:
Waschbisch, Anne, et al. "Demyelinating disease and anti-N-methyl-D-aspartate receptor immunoglobulin G antibodies: a case report." BMC Research Notes 7 (2014): 948.
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