Feng X, Clipston N, Brown T, Cooper H, Reuther U, Hirsch A, Derrick PJ, Drewello T (2000)
Publication Type: Journal article, Original article
Publication year: 2000
Original Authors: Feng X., Clipston N., Brown T., Cooper H., Reuther U., Hirsch A., Derrick P.J., Drewello T.
Publisher: Wiley-Blackwell
Book Volume: 14
Pages Range: 368-370
Journal Issue: 5
DOI: 10.1002/(SICI)1097-0231(20000315)14:5<368::AID-RCM836>3.0.CO;2-L
Important parameters to consider when developing a liquid chromatography/mass spectrometry (LC/MS) method are buffer type and concentration, and column geometry. In the work presented here the choice of buffer for the analysis of basic compounds using a polar embedded phase (HyPURITY(TM) ADVANCE) is illustrated for the analysis of tricyclic antidepressants. Method transfer from a 4.6 mm i.d. column to a 2.1 mm i.d. column is demonstrated for the analysis of triazines and anabolic steroids and their metabolites, with no change in selectivity and with added speed of analysis. Analysis of eight β-blockers is achieved in 65 seconds by using a short 30 x 4.6 mm C18 column. (C) 2000 John Wiley and Sons, Ltd.
APA:
Feng, X., Clipston, N., Brown, T., Cooper, H., Reuther, U., Hirsch, A.,... Drewello, T. (2000). Generation and detection of [C59N]+ by laser desorption/ionisation high-field Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry, 14(5), 368-370. https://doi.org/10.1002/(SICI)1097-0231(20000315)14:5<368::AID-RCM836>3.0.CO;2-L
MLA:
Feng, X., et al. "Generation and detection of [C59N]+ by laser desorption/ionisation high-field Fourier transform ion cyclotron resonance mass spectrometry." Rapid Communications in Mass Spectrometry 14.5 (2000): 368-370.
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