Optical nerve identification in head and neck surgery after Er:YAG laser ablation

Journal article


Publication Details

Author(s): Stelzle F, Knipfer C, Bergauer B, Rohde M, Adler W, Tangermann-Gerk K, Nkenke E, Schmidt M
Journal: Lasers in Medical Science
Publication year: 2014
Volume: 29
Journal issue: 5
Pages range: 1641-8
ISSN: 0268-8921


Abstract


Facial nerve function may be hampered by iatrogenic damage during head and neck laser surgery procedures. Optical techniques can serve as a basis for feedback-controlled tissue-specific laser surgery on the jaw bone and the parotid gland. In order to preserve nerve tissue during laser surgery, the alteration of optical tissue properties through laser-tissue interactions have to be taken into account. It was the aim of this study to evaluate the viability of optical tissue differentiation through diffuse reflectance spectroscopy after exposure to laser light as a basis for a feedback system for tissue-specific laser surgery. Spectra of diffuse reflectance (wavelength, 350-650 nm) of nerves, salivary glands, and cortical and cancellous bone of the midfacial region (ex vivo domestic pig heads) were acquired before/after Er:YAG laser (wavelength, 2.94 ?m) ablation (each 16,800 spectra). Principal component analysis was computed followed by quadratic discriminant analysis. The tissue classification performance as well as area under the curve (AUC) sensitivity and specificity for tissue differentiation was assessed before and after laser-tissue exposure. A high classification performance was observed before laser ablation (total error, 7.74 %). Nerve tissue was differentiated from bone and salivary glands with results greater than 0.96 in AUC, sensitivity and specificity. After laser exposure, a total classification error of 18.61 % was observed. The differentiation of nerve tissue was reduced with an AUC of >0.94, sensitivity of >0.95, and specificity >0.87. Er:YAG laser ablation only slightly reduces the differentiation performance through diffuse reflectance in the investigated tissue types. The results show the general viability of diffuse reflectance spectroscopy in identifying neural structures in the vicinity of salivary glands and bone as a basis for nerve preservation during feedback-controlled laser surgery.



FAU Authors / FAU Editors

Adler, Werner PD Dr.
Lehrstuhl für Biometrie und Epidemiologie
Bergauer, Bastian
Mund-, Kiefer- und Gesichtschirurgische Klinik
Knipfer, Christian
Medizinische Fakultät
Stelzle, Florian Prof. Dr. Dr.
Medizinische Fakultät


External institutions with authors

Bayerisches Laserzentrum gemeinnützige Forschungsgesellschaft mbH (BLZ)


How to cite

APA:
Stelzle, F., Knipfer, C., Bergauer, B., Rohde, M., Adler, W., Tangermann-Gerk, K.,... Schmidt, M. (2014). Optical nerve identification in head and neck surgery after Er:YAG laser ablation. Lasers in Medical Science, 29(5), 1641-8. https://dx.doi.org/10.1007/s10103-014-1569-5

MLA:
Stelzle, Florian, et al. "Optical nerve identification in head and neck surgery after Er:YAG laser ablation." Lasers in Medical Science 29.5 (2014): 1641-8.

BibTeX: 

Last updated on 2018-05-10 at 07:17