Developmental regulation of glycine receptors at efferent synapses of the murine cochlea
Buerbank S, Becker K, Becker CM, Brandt N, Engel J, Knipper M, Schick B, Dlugaiczyk J (2011)
Publication Type: Journal article
Publication year: 2011
Journal
Book Volume: 136
Pages Range: 387-98
Journal Issue: 4
DOI: 10.1007/s00418-011-0855-6
Abstract
Efferent olivocochlear feedback innervation modulates the stream of auditory information from cochlea to brainstem by regulating auditory nerve activity and controlling the contribution of cochlear outer hair cells to basilar membrane motion. In our previous work, we gave a first description of glycine receptors (GlyRs) in the rat cochlea indicating a possible localization at efferent cochlear synapses. Here, we analyze the developmental regulation of GlyR transcripts and protein within the developing murine organ of Corti (postnatal days P0-P21). Using quantitative RT-PCR, GlyR?1 and ?2 were identified as the predominant GlyR? subunit transcripts before the onset of hearing (
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APA:
Buerbank, S., Becker, K., Becker, C.-M., Brandt, N., Engel, J., Knipper, M.,... Dlugaiczyk, J. (2011). Developmental regulation of glycine receptors at efferent synapses of the murine cochlea. Histochemistry and Cell Biology, 136(4), 387-98. https://dx.doi.org/10.1007/s00418-011-0855-6
MLA:
Buerbank, Stefanie, et al. "Developmental regulation of glycine receptors at efferent synapses of the murine cochlea." Histochemistry and Cell Biology 136.4 (2011): 387-98.
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