Radical arylation of tyrosine residues in peptides

Fehler S, Pratsch G, Östreicher C, Fürst M, Pischetsrieder M, Heinrich M (2016)


Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2016

Journal

Publisher: Elsevier Ltd

Book Volume: 72

Pages Range: 7888-7893

Journal Issue: 48

DOI: 10.1016/j.tet.2016.04.084

Abstract

The radical arylation of the phenolic side chain of tyrosine in peptides was investigated. Aryl radicals were generated from aryldiazonium salts using titanium(III) chloride as stoichiometric reductant. Due to the high selectivity with which 3-aryltyrosine derivatives were formed, this reaction type represents a new strategy for the direct functionalization of peptides.

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How to cite

APA:

Fehler, S., Pratsch, G., Östreicher, C., Fürst, M., Pischetsrieder, M., & Heinrich, M. (2016). Radical arylation of tyrosine residues in peptides. Tetrahedron, 72(48), 7888-7893. https://dx.doi.org/10.1016/j.tet.2016.04.084

MLA:

Fehler, Stefanie, et al. "Radical arylation of tyrosine residues in peptides." Tetrahedron 72.48 (2016): 7888-7893.

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